08.06.19
A University of Eastern Finland study published in the American Journal of Clinical Nutrition showed how phosphatidylcholine, an essential nutrient found in eggs and meat, can decrease the chances of developing dementia as well as improve a person’s cognitive performance.
Earlier studies have linked choline intake with cognitive processing, and adequate choline intake may play a role in the prevention of cognitive decline and Alzheimer’s disease. In fact, choline is nowadays used in a multinutrient medical drink intended for the treatment of early Alzheimer’s.
This study showed the risk of dementia was 28% lower in men with the highest intake of dietary phosphatidylcholine, when compared to men with the lowest intake. Men with the highest intake of dietary phosphatidylcholine also excelled in tests measuring their memory and linguistic abilities. These findings are significant since more than 50 million people worldwide are suffering from a memory disorder that has led to dementia, and the number is expected to grow as the population ages. Alzheimer’s disease is the most common cause of dementia, for which no cure currently exists. The new findings may play a vital role in the prevention or delay of dementia, researchers said.
“However, this is just one observational study, and we need further research before any definitive conclusions can be drawn,” Maija Ylilauri, a PhD Student at the University of Eastern Finland pointed out.
The data for the study was derived from the Kuopio Ischaemic Heart Disease Risk Factor Study, KIHD. At the onset of the study in 1984-1989, researchers analyzed approximately 2,500 Finnish men between the ages of 42 and 60 for their dietary and lifestyle habits, and health in general. This data was combined with their hospital records, cause of death records and medication reimbursement records after an average follow-up period of 22 years. In addition, four years after the study onset, approximately 500 men completed tests measuring their memory and cognitive processing. During the follow-up, 337 men developed dementia.
The analysis extensively accounted for other lifestyle and nutrition related factors that could have explained the observed associations. In addition, the APOE4 gene, which predisposes to Alzheimer’s disease and is common in the Finnish population, was accounted for, showing no significant impact on the findings. The key sources of phosphatidylcholine in the study population’s diet were eggs (39%) and meat (37%).
Earlier studies have linked choline intake with cognitive processing, and adequate choline intake may play a role in the prevention of cognitive decline and Alzheimer’s disease. In fact, choline is nowadays used in a multinutrient medical drink intended for the treatment of early Alzheimer’s.
This study showed the risk of dementia was 28% lower in men with the highest intake of dietary phosphatidylcholine, when compared to men with the lowest intake. Men with the highest intake of dietary phosphatidylcholine also excelled in tests measuring their memory and linguistic abilities. These findings are significant since more than 50 million people worldwide are suffering from a memory disorder that has led to dementia, and the number is expected to grow as the population ages. Alzheimer’s disease is the most common cause of dementia, for which no cure currently exists. The new findings may play a vital role in the prevention or delay of dementia, researchers said.
“However, this is just one observational study, and we need further research before any definitive conclusions can be drawn,” Maija Ylilauri, a PhD Student at the University of Eastern Finland pointed out.
The data for the study was derived from the Kuopio Ischaemic Heart Disease Risk Factor Study, KIHD. At the onset of the study in 1984-1989, researchers analyzed approximately 2,500 Finnish men between the ages of 42 and 60 for their dietary and lifestyle habits, and health in general. This data was combined with their hospital records, cause of death records and medication reimbursement records after an average follow-up period of 22 years. In addition, four years after the study onset, approximately 500 men completed tests measuring their memory and cognitive processing. During the follow-up, 337 men developed dementia.
The analysis extensively accounted for other lifestyle and nutrition related factors that could have explained the observed associations. In addition, the APOE4 gene, which predisposes to Alzheimer’s disease and is common in the Finnish population, was accounted for, showing no significant impact on the findings. The key sources of phosphatidylcholine in the study population’s diet were eggs (39%) and meat (37%).
