Mitochondria act as the power producers of cells in the body, and are also involved in other cell processes such as cell division and growth. The enzyme triumvirate, PGC1α-SIRT1-AMPK plays a crucial role in mitochondrial biogenesis and resveratrol aids greatly in the process by enhancing the expression of these three enzymes. BioPerine, by enhancing the bioavailability of resveratrol, plays an amplifying role.
The study was conducted on participants who ingested the combination of resveratrol pus BioPerine for four weeks with moderate exercise. Near infrared spectroscopy was used to study the mitochondrial capacity of wrist flexor muscle of one arm while the other arm served as the control.
“The study is especially significant for the general population who may be unable to perform high intensity exercise,” said Nagabhushanam Kalyanam, PhD, president of R&D, Sabinsa. “Functionally beneficial mitochondrial-performance is realized even with low intensity exercise with resveratrol plus BioPerine supplementation.”
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