In the results of a randomized double blind, placebo-controlled study, published in the Journal of Pharmacy and Nutrition Sciences, UC Davis researchers describe how grape seed extract significantly lowered systolic and diastolic blood pressure among 32 pre-hypertensive adults after just eight weeks. MegaNatural-BP was chosen for use in this study. “This study showed that the extract when administered orally at a dose of 300 mg daily resulted in a significant reduction in blood pressure,” commented lead researcher C. Tissa Kappagoda, professor, director Cardiac Rehabilitation Program, UC Davis.
In the second study, UC Davis researchers investigated whether MegaNatural-Gold Grape Seed Extract, which is rich in mono-, oligo- and poly-metric polyphenols, would modify post-meal oxidative stress and inflammation among adults diagnosed with metabolic syndrome. The results of the randomized, crossover, placebo-controlled study were published in the journal Functional Foods in Health and Disease.
In the study, 12 individuals were randomized to receive either grape seed extract or a placebo approximately one hour before eating a high-fat, high-carb breakfast containing approximately 670 calories, 40% of which were from fat. This breakfast mimics the typical Westernized eating patterns, which are associated with such chronic diseases as diabetes and cardiovascular disease. Participants who received the grape seed extract had improved antioxidant status and experienced reduced blood sugar spikes after their meal.
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