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    Supplier Research

    GanedenBC30 Improves C. Difficile-Induced Colitis

    ...

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    12.12.11
    Researchers from Ganeden Biotech and Penn State College of Medicine have found that the patented probiotic GanedenBC30 has prolonged the survival of, and improved the stool consistency of, Clostridium difficile-induced colitis in mice. The study was published in the November 2011 issue of Gut Pathogens.

    Clostridium difficile (C. diff) is a bacterium that causes inflammation of the colon, known as colitis. People who have other illnesses or conditions requiring prolonged use of antibiotics, and the elderly, are at greater risk of acquiring C. diff.

    “Some previous clinical studies focused on combined treatment with vancomycin and probiotics,” said Leo Fitzpatrick, PhD, lead principal investigator of the study and associate professor of pharmacology at Penn State College of Medicine. “But in this study, administering only GanedenBC30 to C. diff-infected mice resulted in an improvement in the consistency of their stool and reduction in the severity of the disease. This information is particularly helpful and potentially applicable for individuals going into the hospital or a nursing home, where the likelihood of obtaining this disease is higher.” For further information: www.ganedenlabs.com
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