07.12.11
Results of a new preclinical study on Superba Krill Oil, from Aker BioMarine showed a significantly higher impact on gene regulation in the liver when the omega 3 fatty acids were given in the form of phospholipids (krill oil), compared to the triglyceride form (fish oil).
More specifically, krill oil down-regulated the activity of pathways involved in hepatic glucose production as well as lipid and cholesterol synthesis. The data also suggested krill oil-supplementation increases the activity of the mitochondrial respiratory chain. Neither diet elicited changes in plasma levels of lipids, glucose or insulin, probably because the mice used in this study were young and were fed a low fat diet.
The study, published in Frontiers in Nutrigenomics, investigated the regulation of 20,118 genes in mouse livers. Mice were given three different diets for three months: one control diet, one diet supplemented with krill oil and one diet supplemented with fish oil. The diets supplemented with omega 3 contained the same level of the two omega 3 fatty acids EPA and DHA.
Due to the interesting findings in the reported study, Aker BioMarine has now initiated a study where the effects on hepatic lipid, glucose metabolism and mitochondrial function will be studied in more detail. For further information: www.akerbiomarine.com
More specifically, krill oil down-regulated the activity of pathways involved in hepatic glucose production as well as lipid and cholesterol synthesis. The data also suggested krill oil-supplementation increases the activity of the mitochondrial respiratory chain. Neither diet elicited changes in plasma levels of lipids, glucose or insulin, probably because the mice used in this study were young and were fed a low fat diet.
The study, published in Frontiers in Nutrigenomics, investigated the regulation of 20,118 genes in mouse livers. Mice were given three different diets for three months: one control diet, one diet supplemented with krill oil and one diet supplemented with fish oil. The diets supplemented with omega 3 contained the same level of the two omega 3 fatty acids EPA and DHA.
Due to the interesting findings in the reported study, Aker BioMarine has now initiated a study where the effects on hepatic lipid, glucose metabolism and mitochondrial function will be studied in more detail. For further information: www.akerbiomarine.com