06.10.10
A new study involving Institut Rosell-Lallemand’s probiotic Probio’Stick strengthens the idea of a role for the gut microflora and probiotics in the gut brain-axis, or gut-brain communication, indicating potential applications for probiotics in mental health and the management of stress and anxiety.
In this new study, the research team led by looked at the effects of the probiotic preparation Probio’Stick (Lactobacillus Rosell-52 and Bifidobacterium Rosell-175) on rats’ behavioral signs of depression—using social interaction, forced swimming and passive avoidance tests—two weeks following induction of myocardial infarction. They also studied the effects of the probiotic on pro-inflammatory cytokine content as well as on the intestinal barrier integrity.
While rats on control diet showed behavioral signs of depression, the probiotic treatment was able to significantly reduce these signs. Probio’Stick also prevented the post‐MI increase of pro-inflammatory cytokine IL-1β, which is one of the mechanisms involved in the onset of post-MI depression via induction of apoptosis, or programmed cell death, in certain parts of the brain.
Interestingly, this study also showed that myocardial infarction has a detrimental effect on the intestinal barrier and that the probiotic was able to restore its integrity. For further information: www.institut-rosell-lallemand.com
In this new study, the research team led by looked at the effects of the probiotic preparation Probio’Stick (Lactobacillus Rosell-52 and Bifidobacterium Rosell-175) on rats’ behavioral signs of depression—using social interaction, forced swimming and passive avoidance tests—two weeks following induction of myocardial infarction. They also studied the effects of the probiotic on pro-inflammatory cytokine content as well as on the intestinal barrier integrity.
While rats on control diet showed behavioral signs of depression, the probiotic treatment was able to significantly reduce these signs. Probio’Stick also prevented the post‐MI increase of pro-inflammatory cytokine IL-1β, which is one of the mechanisms involved in the onset of post-MI depression via induction of apoptosis, or programmed cell death, in certain parts of the brain.
Interestingly, this study also showed that myocardial infarction has a detrimental effect on the intestinal barrier and that the probiotic was able to restore its integrity. For further information: www.institut-rosell-lallemand.com