Indication: Colorectal cancer
Source: J Natl Cancer Inst., May 5, 2010;102(9):583-5.
Research: Investigators examined the association between dietary fiber intake and colorectal cancer risk by conducting a prospective case-control study nested within seven U.K. cohort studies, which included 579 case patients who developed incident colorectal cancer and 1996 matched control subjects. They used standardized dietary data obtained from 4- to 7-day food diaries that were completed by all participants to calculate the odds ratios for colorectal, colon and rectal cancers. They also calculated odds ratios for colorectal cancer by using dietary data obtained from food-frequency questionnaires that were completed by most participants.
Results: Intakes of absolute fiber and of fiber intake density, ascertained by food diaries, were statistically significantly inversely associated with the risks of colorectal and colon cancers. However, no statistically significant association was observed when the same analysis was conducted using dietary data obtained by food-frequency questionnaire.