05.01.09
Indication: Dementia
Source: Arch Neurol, February 2009;66:216-225.
Research: Investigators calculated a score for adherence to the Mediterranean diet among 1393 individuals with no cognitive problems and 482 patients with mild cognitive impairment. Participants were originally examined, interviewed, screened for cognitive impairments and asked to complete a food frequency questionnaire between 1992 and 1999.
Results: After an average of 4.5 years of follow-up, 275 of the 1393 who did not have mild cognitive impairment developed the condition. Compared with the one-third who had the lowest scores for Mediterranean diet adherence, the one-third with the highest scores for Mediterranean diet adherence had a 28% lower risk of developing mild cognitive impairment and the one-third in the middle group for Mediterranean diet adherence had a 17% lower risk. Among the 482 with mild cognitive impairment at the beginning of the study, 106 developed Alzheimer’s disease over an average of a little more than 4 years of follow-up. Adhering to the Mediterranean diet also was associated with a lower risk for this transition. The one-third of participants with the highest scores for Mediterranean diet adherence had 48% less risk and those in the middle one-third of Mediterranean diet adherence had 45% less risk than the one-third with the lowest scores.
Source: Arch Neurol, February 2009;66:216-225.
Research: Investigators calculated a score for adherence to the Mediterranean diet among 1393 individuals with no cognitive problems and 482 patients with mild cognitive impairment. Participants were originally examined, interviewed, screened for cognitive impairments and asked to complete a food frequency questionnaire between 1992 and 1999.
Results: After an average of 4.5 years of follow-up, 275 of the 1393 who did not have mild cognitive impairment developed the condition. Compared with the one-third who had the lowest scores for Mediterranean diet adherence, the one-third with the highest scores for Mediterranean diet adherence had a 28% lower risk of developing mild cognitive impairment and the one-third in the middle group for Mediterranean diet adherence had a 17% lower risk. Among the 482 with mild cognitive impairment at the beginning of the study, 106 developed Alzheimer’s disease over an average of a little more than 4 years of follow-up. Adhering to the Mediterranean diet also was associated with a lower risk for this transition. The one-third of participants with the highest scores for Mediterranean diet adherence had 48% less risk and those in the middle one-third of Mediterranean diet adherence had 45% less risk than the one-third with the lowest scores.
