The Australian Commonwealth Scientific and Research Organization (CSIRO) Food Futures Flagship has developed an automated instrument for accurately predicting glycemic index (GI) and resistant starch (RS) in food products. The prototype device is an in vitro (bench top) robotic machine that acts as an “artificial gut” to process large numbers of food samples at a fraction of the time and cost required by the standard in vivo (human) method. Its principal purpose is to help food manufacturers develop a wider range of healthy food products far more cheaply and quickly. The CSIRO validation program for the instrument has involved the testing of a range of commercial foods with a wide spectrum of GI and RS values. The results have been benchmarked against “gold standard” human-based tests on the same foods.