10.01.08
A new study released by the University of Connecticut and published in Phytomedicine suggests supplementation with Carnipure, which is manufactured by Lonza, can slow bone loss and improve bone microstructural properties by decreasing bone turnover in aged ovariectomized rats.
For this trial, ovariectomized female rats were assigned to two different groups—one received a diet without L-carnitine supplementation and the other received the same diet plus Carnipure during a 5-week period. Different dietary treatments did not significantly affect food intake or body weight, although there was a tendency of lower body weight in the Carnipure supplemented group. Mean tibial bone mineral density of the Carnipure supplemented rats was significantly higher, over 6% compared to the control group.
This is considered clinically relevant when comparing the results with certain approved medications for osteoporosis. Carnipure supplementation was also found to decrease gene expressions of TRAP, a measure of bone resorption, by nearly 73% while also decreasing two markers of bone formation by over 60%, compared with the control group. According to these findings, researchers believe Carnipure supplementation can suppress the rate of bone turnover.
For further information: 201-316-9413.
For this trial, ovariectomized female rats were assigned to two different groups—one received a diet without L-carnitine supplementation and the other received the same diet plus Carnipure during a 5-week period. Different dietary treatments did not significantly affect food intake or body weight, although there was a tendency of lower body weight in the Carnipure supplemented group. Mean tibial bone mineral density of the Carnipure supplemented rats was significantly higher, over 6% compared to the control group.
This is considered clinically relevant when comparing the results with certain approved medications for osteoporosis. Carnipure supplementation was also found to decrease gene expressions of TRAP, a measure of bone resorption, by nearly 73% while also decreasing two markers of bone formation by over 60%, compared with the control group. According to these findings, researchers believe Carnipure supplementation can suppress the rate of bone turnover.
For further information: 201-316-9413.