10.01.07
The results of a clinical trial investigating the effects of Jarrow Formulas’ (Los Angeles, CA) Bone-Up, an enhanced calcium formula, have been published in the Journal of Nutritional & Environmental Medicine. The study showed that exercise plus intake of Bone-Up can improve bone health in young adult women, which could lower the risk of developing osteoporosis later in life.
An 8-week double-blind, placebo-controlled study using 24 female students ages 18 to 24 was conducted under the direction of Robert DiSilvestro, PhD, at The Ohio State University. Female students who had not done recent, regular resistance exercise followed an 8-week resistance exercise program and also consumed either a placebo or Bone-Up (about 12 subjects per group).
Upon comparing data from before and after the 8-week study intervention, Bone-Up treatment (not placebo) was found to produce statistically significant changes in urinary DPD and alpha-helical peptide (markers of bone degradation), plasma bone specific alkaline phosphatase (a marker of bone synthesis), plasma 2,5-OH-vitamin D (an indicator of vitamin D nutritional status) and plasma parathyroid hormone (a hormone that affects bone metabolism and is affected by calcium nutritional status).
“Observing these positive results in a younger patient population has significant implications for the importance of sufficient dietary bone-building nutrients as part of a life-long approach to the reduction of osteoporosis risk after menopause,” said Kevin Connolly, PhD, director, Research and Development, Jarrow Formulas.
Bone-Up features Australian bovine bone hydroxyapatite, which is the same form of calcium found in human bone tissue—however, it has not been ashed or subjected to any chemical solvents. The product also features vitamins C, D3 and K1, as well as MK-7, folic acid, methyl B-12, magnesium, zinc, manganese, copper, boron and glucosamine.
An 8-week double-blind, placebo-controlled study using 24 female students ages 18 to 24 was conducted under the direction of Robert DiSilvestro, PhD, at The Ohio State University. Female students who had not done recent, regular resistance exercise followed an 8-week resistance exercise program and also consumed either a placebo or Bone-Up (about 12 subjects per group).
Upon comparing data from before and after the 8-week study intervention, Bone-Up treatment (not placebo) was found to produce statistically significant changes in urinary DPD and alpha-helical peptide (markers of bone degradation), plasma bone specific alkaline phosphatase (a marker of bone synthesis), plasma 2,5-OH-vitamin D (an indicator of vitamin D nutritional status) and plasma parathyroid hormone (a hormone that affects bone metabolism and is affected by calcium nutritional status).
“Observing these positive results in a younger patient population has significant implications for the importance of sufficient dietary bone-building nutrients as part of a life-long approach to the reduction of osteoporosis risk after menopause,” said Kevin Connolly, PhD, director, Research and Development, Jarrow Formulas.
Bone-Up features Australian bovine bone hydroxyapatite, which is the same form of calcium found in human bone tissue—however, it has not been ashed or subjected to any chemical solvents. The product also features vitamins C, D3 and K1, as well as MK-7, folic acid, methyl B-12, magnesium, zinc, manganese, copper, boron and glucosamine.