05.01.07
NutraCea, El Dorado Hills, CA, has released the results of a study investigating the effect of rice bran on several intestinal adenomas in cancerous mice. The results were published in the January 9, 2007 online edition of the British Journal of Cancer. The controlled study demonstrated that by consuming a suitable daily dose of stabilized rice bran, an average 51% reduction in the number of precancerous adenomas in the stomach and large intestine of mice was observed.
Prof. Andreas Gescher of the University of Leicester in the U.K., the principal investigator, shared his thoughts on the study. “We compared the cancer-preventive efficacy of NutraCea Stabilized Rice Bran in mouse models of prostate, breast and intestinal cancers. These mice ate a diet containing 30% rice bran. Whilst there was no effect of rice bran on the development of prostate or breast cancer, rice bran significantly retarded the development of adenomas in so-called ‘Min mice,’ a mouse strain that is prone to getting intestinal adenomas. The effect was dependent on the fiber content of the bran. The dose, which was efficacious in these mice translates into approximately 200 grams of rice bran per day in humans,” he said. “Some scientists believe that Min mice serve as a reasonable model of early stages of colorectal cancer in humans. Therefore, we feel that to study the potential colorectal cancer-preventing properties of stabilized rice bran in humans may be a promising idea.”
Prof. Andreas Gescher of the University of Leicester in the U.K., the principal investigator, shared his thoughts on the study. “We compared the cancer-preventive efficacy of NutraCea Stabilized Rice Bran in mouse models of prostate, breast and intestinal cancers. These mice ate a diet containing 30% rice bran. Whilst there was no effect of rice bran on the development of prostate or breast cancer, rice bran significantly retarded the development of adenomas in so-called ‘Min mice,’ a mouse strain that is prone to getting intestinal adenomas. The effect was dependent on the fiber content of the bran. The dose, which was efficacious in these mice translates into approximately 200 grams of rice bran per day in humans,” he said. “Some scientists believe that Min mice serve as a reasonable model of early stages of colorectal cancer in humans. Therefore, we feel that to study the potential colorectal cancer-preventing properties of stabilized rice bran in humans may be a promising idea.”