05.01.02
PC-SPES Analysis
Confirms Presence Of Synthetic Compounds
A two-year study presented at the 93rd Annual Meeting of the American Association for Cancer Research (AACR) has confirmed the presence of synthetic compounds including the estrogenic drug diethylstilbestrol (DES) in PC-SPES, the herbal supplement used by prostate cancer patients. Investigators uncovered the presence of DES, as well as the blood thinner warfarin and the anti-inflammatory drug indomethacin in samples of PC-SPES manufactured from 1996 through 2001. The researchers used HPLC analysis to isolate each unique chemical constituent found in PC-SPES. Researchers also turned their attention to characterizing the biological activity of PC-SPES. By examining the relationship between its composition and its estrogen-like properties, the HPLC findings were then compared with the product's capacity to inhibit the growth of prostate cancer cells in the test tube. The greatest degree of biological activity was found in those samples of PC-SPES that contained the highest concentrations of DES.
Confirms Presence Of Synthetic Compounds
A two-year study presented at the 93rd Annual Meeting of the American Association for Cancer Research (AACR) has confirmed the presence of synthetic compounds including the estrogenic drug diethylstilbestrol (DES) in PC-SPES, the herbal supplement used by prostate cancer patients. Investigators uncovered the presence of DES, as well as the blood thinner warfarin and the anti-inflammatory drug indomethacin in samples of PC-SPES manufactured from 1996 through 2001. The researchers used HPLC analysis to isolate each unique chemical constituent found in PC-SPES. Researchers also turned their attention to characterizing the biological activity of PC-SPES. By examining the relationship between its composition and its estrogen-like properties, the HPLC findings were then compared with the product's capacity to inhibit the growth of prostate cancer cells in the test tube. The greatest degree of biological activity was found in those samples of PC-SPES that contained the highest concentrations of DES.