Access the latest issue of Nutraceuticals World and browse our extensive archives to catch up on past articles and features.
Read the full digital edition of Nutraceuticals World, complete with interactive content and enhanced features for an engaging experience.
Join our community! Subscribe to Nutraceuticals World to receive the latest industry news, insights, and updates directly to your mailbox.
Learn about Nutraceuticals World’s mission, vision, and commitment to providing valuable information and resources for the nutraceutical industry.
Discover advertising opportunities with Nutraceuticals World to connect with a targeted audience in the nutraceutical sector.
Review our editorial guidelines for contributions and submissions to ensure your content aligns with our standards.
Read about our commitment to protecting your privacy and how we handle your personal information.
Familiarize yourself with the terms and conditions governing the use of nutraceuticalsworld.com.
Dive into feature articles that provide in-depth analysis and discussions on critical topics within the nutraceutical space.
Access unique content and exclusive interviews with industry leaders and innovators, offering insights into the future of nutraceuticals.
Discover the top companies in the nutraceutical industry, highlighting their innovations and contributions to the market.
Gain valuable perspectives from suppliers on market trends, challenges, and opportunities within the nutraceutical sector.
Stay informed with regular market updates that track the latest trends and developments impacting the nutraceutical industry.
Explore mergers and acquisitions, financial performance, and investment trends shaping the nutraceutical landscape.
Learn about the latest innovations in manufacturing and formulation processes that enhance product quality and efficacy.
Discover new products and ingredients making waves in the nutraceutical market, along with their benefits and applications.
Stay updated on regulatory developments and compliance issues affecting the nutraceutical industry.
Access the latest research findings and studies that inform trends and innovations in nutraceuticals.
Learn about nutraceutical products that support beauty and wellness, focusing on ingredients that address age-related concerns.
Discover nutraceutical solutions aimed at supporting bone, joint, and muscle health for optimal mobility.
Stay informed on products and ingredients promoting cardiovascular health and wellbeing.
Explore nutraceutical options designed to support the health and development of children.
Learn about nutraceutical products that enhance cognitive function and mental clarity.
Discover nutraceutical solutions that boost energy levels and support overall vitality.
Stay updated on ingredients and products promoting eye health and vision wellness.
Explore nutraceutical offerings tailored specifically for men’s health and wellness.
Learn about nutraceuticals that promote relaxation, stress relief, and improved sleep quality.
Stay informed about antioxidant-rich ingredients that combat oxidative stress and promote overall health.
Explore the benefits of green ingredients, including superfoods and their roles in health and wellness.
Learn about the uses and benefits of herbs, botanicals, and mushrooms in the nutraceutical sector.
Discover the health benefits of omega-3s and other nutritional oils for overall wellbeing.
Stay updated on the latest research and products related to probiotics and prebiotics.
Explore the role of protein and fiber in nutrition and their importance in dietary supplements.
Learn about alternative sweeteners and their applications in the nutraceutical market.
Discover essential vitamins and minerals that support health and wellbeing in various products.
Access our buyer’s guide to find trusted suppliers and service providers in the nutraceutical market.
Identify the top companies leading the nutraceutical industry with innovative products and solutions.
Explore the capabilities of leading nutraceutical companies and their areas of expertise.
Familiarize yourself with key terms and definitions related to the nutraceutical industry.
Watch informative videos featuring industry experts discussing trends, innovations, and insights in nutraceuticals.
Enjoy short, engaging videos that provide quick insights and updates on key nutraceutical topics.
Tune in to discussions with industry leaders sharing their perspectives on trends and challenges in the nutraceutical sector.
Access comprehensive eBooks covering various topics in nutraceuticals, from formulation to marketing.
Read in-depth whitepapers that examine key issues, trends, and research findings in the nutraceutical industry.
Explore informational brochures that provide insights into specific products, companies, and market trends.
Access sponsored articles and insights from leading companies in the nutraceutical sector.
Stay informed with the latest news releases and announcements from companies in the nutraceutical industry.
Browse job opportunities in the nutraceutical sector, connecting you with potential employers.
Discover major industry events, trade shows, and conferences focused on nutraceuticals and dietary supplements.
Participate in informative webinars led by industry experts, covering various topics in nutraceuticals.
Discover exclusive live streams and updates from the hottest events and shows.
What are you searching for?
A 15 mg dose of CBD with or without other cannabinoids improved sleep about as significantly as a 5-mg dose of melatonin.
July 10, 2023
By: Mike Montemarano
Associate Editor, Nutraceuticals World
Cannabidiol (CBD), with or without the use of other minor cannabinoids including cannabinol (CBN) and cannabichromene (CBC), may help to improve sleep disturbances about as much as melatonin in a study published in the Journal of the American Nutrition Association. The study was conducted by contract research organization Radicle Science with materials provided by cannabinoid company Open Book Extracts. A total of 1,298 participants who reported experiencing sleep disturbances at baseline were randomly assigned to take a 4-week supply of either 15 mg of CBD or 5 mg of melatonin alone, or a combination such as CBD/CBN, CBD/CBC, melatonin/CBD, and melatonin/CBD/CBN. Nicole Brown, chief innovation officer at OBX, said the CBN and CBC were selected due to their prominence in the market compared to other minor cannabinoids, as well as their possible potentiating roles in sleep support applications. “The existing literature on CBN suggests that there may be some relaxing and sleep-supporting qualities to it, and CBC is thought to have a potentiating effect where when included in a formula, it can enhance the other cannabinoids in the formulation. It’s encouraging to see the synergy and relationship between minor cannabinoids displayed in this study, especially for the development of full-spectrum products.” Sleep disturbances were measured over a period of 5 weeks, including a baseline week at the beginning of the study prior to product use, via online participation in a questionnaire which measured PROMIS Sleep Disturbance indices. All formulations were found to be safe, with 12% of participants reporting non-severe side effects, and all significantly improved sleep disturbances according to PROMIS scores. There were no significant differences in effects between CBD on its own or in combination with CBN or CBC, or between these three groups and the melatonin group. While melatonin combined with CBD and CBN had the greatest impact on sleep disturbance, it was not significantly greater than that achieved by any of the CBD groups. At baseline, 37%, 23%, 32%, and 8% of participants had slight, mild, moderate, and severe sleep disturbances, respectively. By the end of the study, 67% of participants in total experienced a minimal clinically important difference (MCID) in PROMIS sleep quality stores. “Notably, all study arms led to significant improvements in sleep disturbance and exhibited favorable safety profiles,” the authors wrote.
Enter your account email.
A verification code was sent to your email, Enter the 6-digit code sent to your mail.
Didn't get the code? Check your spam folder or resend code
Set a new password for signing in and accessing your data.
Your Password has been Updated !