02.22.08
Indication: Urinary tract infections (UTIs)
Source: Cochrane Library, Online January 22, 2008
Research: Analyzing 10 previous studies, researchers assessed whether or not cranberries can help prevent or treat urinary tract infections (UTIs). Researchers conducted a meta-analysis on all randomized controlled trials (RCTs) or quasi-RCTs of cranberry products for the prevention of UTIs in all populations. Information was collected on methods, participants, interventions and outcomes. The 10 studies-five cross-over, five parallel group-included 1049 subjects. Cranberry/cranberry-lingonberry juice versus placebo, juice or water was evaluated in seven studies, and cranberry tablets versus placebo in 4 studies (one study evaluated both juice and tablets).
Results: The authors believe there is some evidence that cranberry juice may decrease the number of symptomatic UTIs over a 12-month period, particularly for women with recurrent UTIs. However, its effectiveness for other groups is less certain. The large number of dropouts/withdrawals indicates that cranberry juice may not be acceptable over long periods of time. It is not clear what is the optimum dosage or method of administration (e.g. juice, tablets or capsules), which is why they suggest the need for properly designed studies with relevant outcomes.