Peer-reviewed Research

Lignans

Indication:

Breast health

Source:

Eur J Cancer Prev, June 2006;15(3):225-232.

Research:

In this study, researchers measured enterolactone (the bioactive lignan metabolite in humans) and genistein levels in 220 premenopausal women and 237 age-matched controls.

Results:

The median levels of plasma enterolactone in the case group were 6.3 nmol/l, compared to 9.7 nmol/l in the control group, while median genistein levels were a respective 4.5 and 3.7 nmol/l. The researchers noted a decrease in pre-menopausal breast cancer risk in tandem with increased concentrations of plasma enterolactone. There was no such significant association noted with genistein, and the study authors concluded that using biomarkers of phytoestrogen intake, we confirmed the strong inverse association between enterolactone and premenopausal breast cancer risk as found with dietary intake estimates. This result gives support to the potential role of mammalian lignans for breast cancer prevention among premenopausal women in Western populations.

Related Peer-reviewed Research

Cancer Risk | Research | Research News | Testing | Women's Health

Flavonoids: Ovarian Cancer

Nutraceutical: Flavonoids Indication: Ovarian Cancer Source: American Journal of Clinical Nutrition, October 2014 Research: The impact of different dietary flavonoid subclasses on risk of epithelial ovarian cancer is unclear, with limited pr…
12.01.14
Cancer Risk | Fatty Acids | Research | Research News | Women's Health

Omega 3 Polyunsaturated Fatty Acids: Breast Cancer Risk

Nutraceutical: Omega 3 Polyunsaturated fatty acids Indication: Breast Cancer Risk Source: British Medical Journal 2013;346:f3706 Research: The objective of this meta-analysis and systematic review of prospective cohort studies was to investiga…
10.01.13
Cancer Risk | Fatty Acids | Research | Research News | Testing | Women's Health

Omega 3 Fatty Acids: Breast Cancer Risk

Nutraceutical: Omega 3 Fatty Acids Indication: Breast Cancer Risk Source: British Medical Journal June 2013; 346:f3706 Research: This study investigated the association between intake of fish and omega 3 polyunsaturated fatty acids (n-3 PUFA) and…
09.09.13
Cancer Risk | Research | Research News | Women's Health

Vitamin B6: Breast cancer

Nutraceutical: Vitamin B6 Indication: Breast cancer Source: Cancer Epidemiology, Biomarkers, and Prevention, August 9, 2012;[Epub ahead of print] Research: Researchers examined the association of pre-diagnostic plasma concen…
10.01.12
Cancer Risk | Research | Research News

Vitamin E: Liver cancer

Nutraceutical: Vitamin E Indication: Liver cancer Source: J Natl Cancer Inst, August 8, 2012;104(15):1174-82. Research: To determine the relationship between vitamin E intake and liver cancer risk researchers analyzed…
10.01.12
Cancer Risk | Fatty Acids | Research News | Vitamins

Omega 3s, B Vitamins: Cancer prevention

Nutraceutical: Omega 3s, B vitamins Indication: Cancer prevention Source: Arch Intern Med, February 13, 2012; [Epub ahead of print]: doi:10.1001/archinternmed.2011.1450 Research: Researchers investigated the effects of B vitamin and/or omega 3 fat…
04.01.12
Cancer Risk | Men's Health | Research | Research News

Vitamin E: Prostate cancer

Nutraceutical: Vitamin E Indication: Prostate cancer Source: JAMA, October 12, 2011;306(14): 1549-56. Research: The initial report of the Selenium and Vitamin E Cancer Prevention Trial (SELECT) found no reduction in risk of prostate cancer with ei…
03.01.12
Cancer Risk | Fatty Acids | Inflammation | Men's Health | Research | Research News | Sexual & Reproductive Health

Omega 3 DHA: Prostate Cancer

Nutraceutical: Omega 3 DHA Indication: Prostate cancer Source: Am J Clin Epidemiol, April 25, 2011; [Epub ahead of print]. Research: Inflammation may be involved in prostate cancer development and progression, so researchers exam…
06.01.11
Cancer Risk | Digestive Health | Research | Research News

Fiber: Colorectal cancer

Nutraceutical: Fiber Indication: Colorectal cancer Source: J Natl Cancer Inst., May 5, 2010;102(9):583-5. Research: Investigators examined the association between dietary fiber intake and colorectal cancer risk by con…
06.01.10
Cancer Risk | Research | Research News

Vitamin D: Colorectal cancer

Nutraceutical: Vitamin D Indication: Colorectal cancer Source: BMJ, January 21, 2010;340:b5500. Research: Researchers set out to examine the association between pre-diagnostic circulating vitamin D concentration, dietary intake of vitamin D and c…
04.01.10
Antioxidants | Cancer Risk | Fatty Acids | Men's Health | Research | Research News | Vitamins

Antioxidants and fatty acids: Pancreatic cancer

Nutraceutical(s): Antioxidants and fatty acids Indication: Pancreatic cancer Source: Int J Cancer, January 26, 2010 [Epub ahead of print]. Research: Since there are no well-established modifiable risk factors for pancreatic cancer except smoking,…
03.01.10
Cancer Risk | Research News | Vitamins

Folic acid/folate

Indication: Breast cancer Source: American Journal of Clinical Nutrition, 2009;89(2):624-33. Research: Folic acid (also known as folate) is a member of the water-soluble B vitamin group. It is also one of the most common vitamin deficiencies. R…
12.01.09
Cancer Risk | Fatty Acids | Research News

Omega 3s

Indication: Breast cancer Source: BMC Cancer, June 30, 2009;9:216. Research: Although it is believed that fish omega 3 fatty acids may decrease breast cancer risk, epidemiological evidence has been inconclusive. This study examined the asso…
08.27.09
Cancer Risk | Research News

Soy

Indication: Colorectal cancer (postmenopausal women) Source: Am J Clin Nutr, February 2009;89(2):577-83. Research: Soy and some of its constituents, such as isoflavones, have been shown to have cancer-inhibitory activities in experimental stu…
05.01.09
Cancer Risk | Research News

Soy

Indication: Colorectal cancer (postmenopausal women) Source: Am J Clin Nutr, February 2009;89(2):577-83. Research: Soy and some of its constituents, such as isoflavones, have been shown to have cancer-inhibitory activities in experimental stu…
03.23.09