05.17.06
Indication: Pancreatic cancer
Source: J Natl Can Inst, March 15, 2006;98(6):407-413.
Research: Epidemiologic evidence supports an association between high folate intake and reduced risk of some cancers, in particular colorectal cancer. However, epidemiologic data concerning the relationship between folate and pancreatic cancer risk are sparse. So researchers decided to examine the association between folate intake and the risk of pancreatic cancer in a population-based prospective study of Swedish women and men. As such, researchers prospectively followed 81,922 women and men in the Swedish Mammography Cohort and the Cohort of Swedish Men who were cancer-free and completed a 96-item food-frequency questionnaire in 1997.
Results: After almost seven years of follow-up, a total of 135 incident pancreatic cancer cases were diagnosed. In multivariable analyses controlling for age, smoking, fruit and vegetable consumption, and other potential confounders, dietary and total folate intakes were inversely associated with risk of pancreatic cancer. Folic acid from supplements, however, was not associated with pancreatic cancer. These findings led researchers to conclude that increased intake of folate from food sources, but not from supplements, may be associated with a reduced risk of pancreatic cancer.
Source: J Natl Can Inst, March 15, 2006;98(6):407-413.
Research: Epidemiologic evidence supports an association between high folate intake and reduced risk of some cancers, in particular colorectal cancer. However, epidemiologic data concerning the relationship between folate and pancreatic cancer risk are sparse. So researchers decided to examine the association between folate intake and the risk of pancreatic cancer in a population-based prospective study of Swedish women and men. As such, researchers prospectively followed 81,922 women and men in the Swedish Mammography Cohort and the Cohort of Swedish Men who were cancer-free and completed a 96-item food-frequency questionnaire in 1997.
Results: After almost seven years of follow-up, a total of 135 incident pancreatic cancer cases were diagnosed. In multivariable analyses controlling for age, smoking, fruit and vegetable consumption, and other potential confounders, dietary and total folate intakes were inversely associated with risk of pancreatic cancer. Folic acid from supplements, however, was not associated with pancreatic cancer. These findings led researchers to conclude that increased intake of folate from food sources, but not from supplements, may be associated with a reduced risk of pancreatic cancer.
