• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Contract Manufacturing: Trials & Tribulations of Today’s Supply Chains

    Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality

    Nutrition and Flavor: Formulating for Modern Product Preferences

    What Do Consumers Know About the Gut Microbiome?

    How Will the European Green Deal Impact Dietary Supplements?
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market

    Tazo Transitions to Regenerative Organic Agriculture

    Protein Ingredient Formulated for Chronic Kidney Disease Patients

    IADSA Calls for Addressing Discrepancies in Vitamin C Recommendations
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Fact or Myth: Antioxidants Negatively Impact Iron Absorption

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market

    Tazo Transitions to Regenerative Organic Agriculture

    Protein Ingredient Formulated for Chronic Kidney Disease Patients
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Fact or Myth: Antioxidants Negatively Impact Iron Absorption

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market

    Tazo Transitions to Regenerative Organic Agriculture

    Protein Ingredient Formulated for Chronic Kidney Disease Patients
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    Caffeine-Free Energy Supplement Linked to Alertness, Fatigue Benefits

    Monk Fruit Sweetener May Have Prebiotic Activity, Study Finds

    People with Low-Fiber Diets Benefit the Most from Fiber Supplements, Study Finds

    Gut Microbiome May Be Part of Link Between Red Meat and Heart Disease Risk
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Nutrition21, LLC

    PhytoGaia Inc

    Xsto Solutions

    Botanic Healthcare LLC

    KLK OLEO
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Nutrition21, LLC

    PhytoGaia Inc

    Xsto Solutions

    Botanic Healthcare LLC

    KLK OLEO
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Online Exclusives

    Tablet & Capsule Trends

    Companies discuss the latest developments for new, innovative delivery technologies.

    Related CONTENT
    • Food Processing for Health and Wellness
    • Formulating for Nutrient Bioavailability
    • 3i Solutions Announces New Leadership Positions
    • TopGum Gummies Receives USDA Organic Certification
    • Registration Opens for Vitafoods Asia 2022
    Joanna Cosgrove03.01.09

    Tablet & Capsule Trends



    Companies discuss the latest developments for new, innovative delivery technologies.



    By Joanna Cosgrove
    Online Editor




    Tablets and capsules have collectively served the pharmaceutical and nutraceutical industry for about 200 years, however the top issues for manufacturers of these venerable delivery vehicles have remained constant: safety and quality continue to be paramount, perennial concerns.

    These concerns begin with the sourcing of raw ingredients. “The most important issues for Greenwood, SC-based Capsugel are safety and quality of raw ingredients in our products and the uninterrupted flow of product supply to our customers,” said the company’s Mark Vieceli, manager, Marketing and Business Development, Americas region. “We go to great lengths to make sure that the raw ingredients used for making the capsules—gelatins from bovine, porcine or fish sources, pullulan and HPMC—come from appropriate sources that can be traced and documented.”

    Mr. Vieceli continued, “We also have a detailed audit procedure, which ensures our vendor’s processes are appropriate, so that when we receive our raw materials they are up to our standards. We verify that our materials are not adulterated through rigorous testing standards.”

    Andrew Goldman, web marketing manager for Nutricap Labs, Farmingdale, NY, expressed similar thoughts. “[Safety and quality] is especially important when it comes to manufacturing tablets or capsules that need to be organic, vegan, kosher, herbal, all natural, non-allergenic, soy or gluten free,” he said. “Failure to manufacture a product to the exact specifications requested could spell disaster for a product line before it even gets off the ground.”

    The safety and efficacy of capsule and tablet ingredients is especially important because many suppliers manufacture the products for both nutraceutical and more heavily regulated pharmaceutical applications. “We don’t distinguish between the quality of ingredients for capsules used in dietary supplements or pharmaceuticals,” commented Mr. Vieceli. “All are subjected to the same high level of quality and safety standards. We are audited by top multinational pharmaceutical companies. Our goal is to produce safe products because they are used for medicine as well as dietary supplements.”


    Segment Trends



    As marketers look to create differentiation and a more pleasing consumer experience, an important trend impacting the dietary supplement market is the growth and diversity of new solid dosage forms. “Orally Disintegrating Tablets (ODTs) and chewable tablets offer young children, seniors and consumers known to have difficulty swallowing tablets a way to consume tablets virtually the same way as they do food,” said Tim Bee, senior director of pharmaceuticals for International Specialty Products (ISP) Corp., Wayne, NJ.

    ISP’s Polyplasdone XL-10 disintegrant is used in fast melting forms because of its disintegration efficiency and excellent mouthfeel. “When introduced into water, the Polyplasdone XL-10 disintegrant quickly wicks water into the tablet through capillary action, creating the internal pressure that disintegrates the tablet,” explained Mr. Bee. “At the same time, the small particle size and narrow particle size distribution imparts a smooth mouthfeel consumers prefer.”

    Another market trend is the growth in “high nutrient” content nutraceuticals, as developers of these products look to pack ever higher levels of actives into increasingly exotic formulas. “These denser formulas allow less room for binder ingredients and are more difficult to coat,” said Mr. Bee. “High efficiency materials developed by ISP for the pharmaceutical industry are finding their way into these formulas, including Plasdone S-630 Copovidone copolymer, which is self-affirmed GRAS (Generally Recognized As Safe). The chemical structure of the copolymer offers excellent adhesion properties, providing the benefit of efficiency-in-use.”

    According to Mr. Bee, an additional trend pertains to poor solubility of “actives.” “Given that inefficiency in this area is believed to impact the bioavailability of nutrients…particularly with reports in the mass media questioning the efficacy of vitamins and supplements, conscientious producers want to be sure the products they make perform as intended,” he said. “ISP’s Polyplasdone superdisintegrant is relevant to this discussion because it enhances the solubility of poorly soluble actives. Given that bioavailability is often a function of the dissolution rate, it is best to source a disintegrant that provides maximum solubility.”

    One of the hottest trends in encapsulation is controlled-release and multi-release products, which entails putting multiple components in one convenient package. A new product format from Capsugel places beads within a liquid-filled capsule (pictured above). “The liquid dose is designed to offer quick release of an ingredient. The beads provide for a controlled or delayed time release,” said Mr. Vieceli. “The thickness of the bead’s coating can be changed so that some beads dissolve as soon as the capsule ruptures, while other beads dissolve later. The ‘beads-in-a-capsule’ product is also visually attractive—an added boost for product differentiation and instant consumer appeal. This novel design allows companies to design a multitude of looks using colorful beads, as well as colored and printed capsule combinations.”

    Consmer Trends



    Just as consumers are increasingly particular about the types of foods they purchase, they also are more carefully scrutinizing the ingredient panel of their supplements. “They are looking for natural solutions, products without additives and potential allergens, and freshness in food and other products,” said Capsugel’s Mr. Vieceli. “The group that wants vegetarian products continues to grow, even in this economy.”

    To meet the increased demand for clean-label vegetarian capsules, the company is expanding its manufacturing capabilities for its HMPC capsules—a lineup that includes a new 16-color palette of natural colorants for gelatin and HPMC capsules.

    Visual appeal was also a consideration at CapsCanada, which recently launched Platinum Caps, a two-piece capsule with a metallic look. Platinum Caps are available in a range of colors and color combinations (green, red, purple, blue, turquoise, orange, silver, gold, platinum, bronze, etc) in gelatin or vegetable HPMC according to customers’ needs. The metallic look is obtained with a light-reflecting pigment, Candurin, composed of titanium dioxide and natural mica (FDA-approved for use in food and supplements and a registered trademark of Merck KGaA).

    On the tablet front, late last year, ISP introduced a unique solution to improve the efficiency of tablet coating. Called Advantia Preferred HS Coatings, the high solids system offers a very high level of adhesion. “This ‘super adhesion’ capability is significant in that it improves the appearance of tablets, and at the same time, reduces quality problems that may not otherwise be solved easily,” said Mr. Bee. “Advantia Preferred HS coatings are also a time saver. Production-scale coating trials conducted by ISP have demonstrated that spraying Advantia Preferred HS coating suspensions at up to 25% solids translates into a 43% savings in process time over traditional HPMC-based coating suspensions.”

    Enteric coatings are another area of interest. “It’s a longer more costly process however enteric coating breaks down not in the stomach but in the intestines for different absorption,” commented Darren Schneider, vice president, CapsuleWorks, Ronkonkoma, NY.

    Among other trends, Mr. Vieceli reported that the consumer desire for liquid capsule offerings is on the rise. “Tablets and chewables are steadily losing ground as capsules, and liquid-filled capsules in particular, are gaining,” he said. “Our survey of 1500 consumers in 25 markets at the end of 2008 verified this shift over the last five years. The reason is that people want dosage forms that are easier to swallow—and they attribute that to capsules. They also believe that liquid-filled capsules work faster and better.”

    Capsugel manufactures a unique liquid capsule within a capsule, and like the “beads-in-a-capsule” it can combine multiple ingredients with different release profiles in a single dosage as well, including incompatible ingredients that must be delivered at different times and places in the body for optimum impact. The difference is that all the ingredients are in liquid form. “One specific product category that can benefit from a ‘capsule-in-a-capsule’ approach is probiotics,” said Mr. Vieceli. “The Pre-Pro Combo developed by Capsugel, for example, delivers a liquid prebiotic outer layer surrounding a quality probiotic contained in the inner capsule. The design enhances product stability by protecting the probiotic inner capsule in an HPMC capsule suspended in a glycerin formula. This creates an effective barrier to moisture, which helps the probiotic remain inactive until it is ready to go to work in your system.”

    By all accounts, tablet and capsule innovation and manufacturing technologies are on the rise, which will no doubt solidify their position as the go-to delivery format preferred by nutritional supplement consumers.
    Related Searches
    • Dietary Supplements
    • Vitamins
    • Healthcare Trends
    • Delivery & Dosage Technologies
    Related Knowledge Center
    • Dietary Supplements
    • Healthcare Trends
    • Delivery & Dosage Technologies
    Suggested For You
    Food Processing for Health and Wellness Food Processing for Health and Wellness
    Formulating for Nutrient Bioavailability Formulating for Nutrient Bioavailability
    3i Solutions Announces New Leadership Positions 3i Solutions Announces New Leadership Positions
    TopGum Gummies Receives USDA Organic Certification TopGum Gummies Receives USDA Organic Certification
    Registration Opens for Vitafoods Asia 2022 Registration Opens for Vitafoods Asia 2022
    What People Were Reading in July 2022 on NutraceuticalsWorld.com What People Were Reading in July 2022 on NutraceuticalsWorld.com
    Open Book Extracts Expands Capabilities to Boost Finished Products Manufacturing Open Book Extracts Expands Capabilities to Boost Finished Products Manufacturing
    Seaweed Extract Could Offer Gastroenteritis Relief Seaweed Extract Could Offer Gastroenteritis Relief
    Saffron Extract May Offer Mental and Physical Benefits in Active Males Saffron Extract May Offer Mental and Physical Benefits in Active Males
    Substantiating Environmental, Social, and Governance Claims Substantiating Environmental, Social, and Governance Claims
    Medical Food Addresses Fatty Acid Deficiencies, May Help Manage ADHD Symptoms Medical Food Addresses Fatty Acid Deficiencies, May Help Manage ADHD Symptoms
    Thomas Fulfillment Thomas Fulfillment
    Senator Richard Burr Introduces Alternative Legislation Without MPL Provisions Senator Richard Burr Introduces Alternative Legislation Without MPL Provisions
    Get in the game: Join the esports nutrition market Get in the game: Join the esports nutrition market
    Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality

    Related Online Exclusives

    • Delivery & Dosage Technologies | Enzymes | Functional Foods & Beverages | Natural/Organic | Proteins, Peptides, Amino Acids | Research
      Food Processing for Health and Wellness

      Food Processing for Health and Wellness

      At IFT FIRST, a panel of researchers covered the benefits of upcycled materials and sustainable measures to produce health and wellness products.
      By Mike Montemarano, Associate Editor 08.09.22

    • Antioxidants | Delivery & Dosage Technologies | Fiber & Carbohydrates | Functional Foods & Beverages | Research
      Formulating for Nutrient Bioavailability

      Formulating for Nutrient Bioavailability

      At IFT FIRST, food scientists discussed innovation and insights into how we digest, absorb, and utilize nutrients.
      By Mike Montemarano, Associate Editor 08.09.22

    • Breaking News | Contract Manufacturing | Dietary Supplements | People News
      3i Solutions Announces New Leadership Positions

      3i Solutions Announces New Leadership Positions

      Brian Reich and Becky Wagner were hired to two respective new positions, director of finance and director of business development.
      08.05.22


    • Breaking News | Certifications, Approvals & Patents | Contract Manufacturing | Delivery & Dosage Technologies | Dietary Supplements | Natural/Organic
      TopGum Gummies Receives USDA Organic Certification

      TopGum Gummies Receives USDA Organic Certification

      TopGum earned a formal certification through sourcing select and certified organic materials and following strict internal procedures.
      08.03.22

    • Breaking News | Industry & Market News | World Markets
      Registration Opens for Vitafoods Asia 2022

      Registration Opens for Vitafoods Asia 2022

      The event, co-located with Fi Asia, will take place in Bangkok Oct. 5-7.
      08.03.22

    Loading, Please Wait..
    Trending
    • Study Examines Vitamin K2 Content In Cheese
    • Chenland Nutritionals Self-Affirms GRAS For Cumin UP60 Ingredient
    • Pycnogenol Evidenced To Have Skin Benefits In Dermatology Study
    • ADM And Benson Hill Partner To Scale High Protein Soy For U.S. Market
    Breaking News
    • Charlotte’s Web Sports Product Line to Undergo NSF Certification Process
    • ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market
    • Tazo Transitions to Regenerative Organic Agriculture
    • Protein Ingredient Formulated for Chronic Kidney Disease Patients
    • IADSA Calls for Addressing Discrepancies in Vitamin C Recommendations
    View Breaking News >
    CURRENT ISSUE

    July/August 2022

    • A Growing Herbal Products Market Still Faces Formidable Threats, Challenges
    • Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality
    • Nutrition and Flavor: Formulating for Modern Product Preferences
    • Contract Manufacturing: Trials & Tribulations of Today’s Supply Chains
    • How Will the European Green Deal Impact Dietary Supplements?
    • What Do Consumers Know About the Gut Microbiome?
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process
    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market
    Tazo Transitions to Regenerative Organic Agriculture
    Coatings World

    Latest Breaking News From Coatings World

    What are you Reading this Week?
    SONGWON Industrial Group Reports Strong Q2 Financial Results
    PPG Completes COLORFUL COMMUNITIES Project for Boys & Girls Clubs of Greater Houston
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most-Read Stories This Week—Aug. 13
    'Graft-on-a-Chip' Built to Improve Vascular Graft Success
    Abbott Invests €440 in New Irish Facility
    Contract Pharma

    Latest Breaking News From Contract Pharma

    AskBio Appoints Clinical Ops Executives
    SpectrumX Partners With UK Contract Manufacturer
    GL Chemtec Partners with Edgewater Capital to Accelerate Growth
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Arkay Chairman Emeritus Howard Kaneff Has Died
    Nutricosmetics Market to Hit $13.7 Billion by 2030
    Estée Lauder Pledges 100% Electric Fleet of Vehicles by 2030
    Happi

    Latest Breaking News From Happi

    Consumers are Clamoring for Vintage Glam: Spate
    Kayali’s Lovefest Fragrance, Newell’s New Candle and HydraFacial’s Record Financial Results
    Self Care Trumps Home Care Post-Covid
    Ink World

    Latest Breaking News From Ink World

    Weekly Recap: Printing Ink Primer, Zeller+Gmelin Lead This Week’s News Stories
    Heidelberg Enjoys Successful Start to 2022-23 Fiscal Year
    Mimaki Announces New LATAM Website
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Esko, Constantia Flexibles announce acquisitions and more
    Hybrid Software joins The Flexo Xperience Center
    Flexo Wash LLC and Mike Potter celebrate 20 years
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Weekly Recap: Essity Switches to Recyclable Packs for Feminine Pads, FTC Sues PPE Maker on False Origin Claims & More
    Focke & Co. to Host Destination: Your Hygiene Hub on August 31
    Exports Dominate Chinese Trade of Tissues, Hygiene Products and Wipes
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—Aug. 13
    Dental 3D Printing Market is Expanding 20% Annually
    Study Results Released for Abbott's Concussion Blood Test
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Weekly Recap: ALTANA, Universal Display and Emerson Top This Week’s Stories
    eMagin Corporation Announces 2Q 2022 Results
    Zebra Technologies’ Emission Reduction Targets Validated by SBTi

    Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login