09.11.24
Gnosis by Lesaffre sponsored FASEB (Federation of American Societies for Experimental Biology)’s B Vitamins and One-Carbon Metabolism Conference in August.
The company’s research collaborator Teodoro Bottiglieri, PhD, program director of the center for metabolomics at Baylor Scott & White Research Institute, led the panel at the “Advances in Metabolics” workshop.
For over 35 years, FASEB’s conference has been a venue for scientists and clinicians to discuss research on B vitamins and one-carbon metabolism, focusing on recent advances, public health implications, and future collaborations. The program covered a wide range of topics including global deficiencies, impact on fetal and post-natal health, supplementation, roles in epigenomics, and implications for neurological disorders with a focus on cogntion.
"Studying metabolomics in relation to B-vitamins and one-carbon metabolism disorders is important because these pathways are crucial for DNA function and overall health,” said Bottiglieri. “Understanding metabolic changes can lead to earlier diagnoses, better treatments, and improved outcomes for neurodegeneration or cardiovascular diseases. In addition, with the advancements made in analytical technology, we are now beginning to better understand the impact of B-vitamin deficiencies on cellular metabolism that results in specific phenotypic expression in individuals that can lead to appropriate therapeutic interventions.”
In 2019, Bottiglieri received recognition for his monograph, “SAMe: Metabolic Function and Health Benefits,” which he presented at the Integrative Healthcare Symposium in New York. The literature review explored biological roles and benefits of SAMe.
Bottiglieri recently completed a study which discovered that SAMe is present in higher concentrations in breast milk compared to other biofluids, suggesting a crucial role in infant development and important implications for breastfeeding and formulating infant nutrition products.
“We found that SAMe, crucial for metabolic pathways and neurodevelopment, is present in much higher concentrations in breast milk, likely from breast tissue,” Bottiglieri said. “This suggests SAMe plays a vital role in infant growth, but more research is needed to fully understand its significance and potential impact on breastfeeding practices and infant formula compositions.”
“Gnosis is proud to remain at the cutting edge of science, receiving research support for key products in our portfolio, including Quatrefolic® active folate and Adonat® Premium SAMe,” said Jean-François Jeanne, substantiation and applications manager at Gnosis. “Prof. Bottiglieri’s groundbreaking work and voice at the FASEB Conference reinforces what we have been trying to accomplish with our ingredients: identifying opportunities to create a healthier global population through correcting nutrient deficiencies.”
The company’s research collaborator Teodoro Bottiglieri, PhD, program director of the center for metabolomics at Baylor Scott & White Research Institute, led the panel at the “Advances in Metabolics” workshop.
For over 35 years, FASEB’s conference has been a venue for scientists and clinicians to discuss research on B vitamins and one-carbon metabolism, focusing on recent advances, public health implications, and future collaborations. The program covered a wide range of topics including global deficiencies, impact on fetal and post-natal health, supplementation, roles in epigenomics, and implications for neurological disorders with a focus on cogntion.
"Studying metabolomics in relation to B-vitamins and one-carbon metabolism disorders is important because these pathways are crucial for DNA function and overall health,” said Bottiglieri. “Understanding metabolic changes can lead to earlier diagnoses, better treatments, and improved outcomes for neurodegeneration or cardiovascular diseases. In addition, with the advancements made in analytical technology, we are now beginning to better understand the impact of B-vitamin deficiencies on cellular metabolism that results in specific phenotypic expression in individuals that can lead to appropriate therapeutic interventions.”
In 2019, Bottiglieri received recognition for his monograph, “SAMe: Metabolic Function and Health Benefits,” which he presented at the Integrative Healthcare Symposium in New York. The literature review explored biological roles and benefits of SAMe.
Bottiglieri recently completed a study which discovered that SAMe is present in higher concentrations in breast milk compared to other biofluids, suggesting a crucial role in infant development and important implications for breastfeeding and formulating infant nutrition products.
“We found that SAMe, crucial for metabolic pathways and neurodevelopment, is present in much higher concentrations in breast milk, likely from breast tissue,” Bottiglieri said. “This suggests SAMe plays a vital role in infant growth, but more research is needed to fully understand its significance and potential impact on breastfeeding practices and infant formula compositions.”
“Gnosis is proud to remain at the cutting edge of science, receiving research support for key products in our portfolio, including Quatrefolic® active folate and Adonat® Premium SAMe,” said Jean-François Jeanne, substantiation and applications manager at Gnosis. “Prof. Bottiglieri’s groundbreaking work and voice at the FASEB Conference reinforces what we have been trying to accomplish with our ingredients: identifying opportunities to create a healthier global population through correcting nutrient deficiencies.”
