• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    State of the Industry Series (Part 1): FDA Restructuring and FTC Activity

    State of the Industry Part 2: Supplement Access, Safety, and CBD

    State of the Industry Part 3: Communication, Education, and Trust

    State of the Industry Part 4: Advanced/Advancing Technologies and Research

    State of the Industry Part 5: Advocating Best Practices
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Glossary
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Women in Nutraceuticals Hires Executive Director Rebecca Takemoto

    FDA Issues Interim Response to Nammex’s Mushroom Labeling Petition

    MSM Linked to Improvements in Knee Pain

    Lion’s Mane Extract Linked to Better Cognitive Performance, Subjective Stress

    NutraShure Introduces SA3X as Exclusive US Supplier
    Exclusives
    Top Companies
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Lion’s Mane Extract Linked to Better Cognitive Performance, Subjective Stress

    NutraShure Introduces SA3X as Exclusive US Supplier

    Tocotrienol Supplementation May Aid Liver Function in Diabetes, MASL Patients

    Euromed Receives EcoVadis Platinum Medal for ESG Efforts

    State of the Industry Part 2: Supplement Access, Safety, and CBD
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    FDA Issues Interim Response to Nammex’s Mushroom Labeling Petition

    MSM Linked to Improvements in Knee Pain

    Lion’s Mane Extract Linked to Better Cognitive Performance, Subjective Stress

    NPA Lawsuit Claims New York Age Restriction on Supplements is Unconstitutional

    Kyowa Hakko Publishes First Report on Global Health, Sustainability Impact
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    MSM Linked to Improvements in Knee Pain

    Lion’s Mane Extract Linked to Better Cognitive Performance, Subjective Stress

    NutraShure Introduces SA3X as Exclusive US Supplier

    NPA Lawsuit Claims New York Age Restriction on Supplements is Unconstitutional

    Gencor’s PEA Ingredient Levagen+ May Offer Allergy Relief
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Premium Labels & Packaging Solutions

    Bioenergy Life Science, Inc. (BLS)

    PhytoGaia Inc

    Kaneka Nutrients

    American FlexPack
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Premium Labels & Packaging Solutions

    Bioenergy Life Science, Inc. (BLS)

    PhytoGaia Inc

    Kaneka Nutrients

    American FlexPack
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Top Companies
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    HMB Supplementation May Benefit Delayed-Onset Muscle Soreness

    The amino acid metabolite was tested in a population of 24 professional soccer players.

    HMB Supplementation May Benefit Delayed-Onset Muscle Soreness
    06.10.22
    Supplementing with HMB, a metabolite of the amino acid leucine, was linked to reduced delayed-onset muscle soreness (DOMS) in a study conducted on 24 professional soccer players. The study appeared in the Journal of Pharmaceutical Negative Results.
     
    In the study, the researchers recruited a population of 24 professional soccer players who either took a placebo or a daily supplement containing three grams of HMB-FA for two days, once each before a high-intensity resistance training session. Before supplementation and immediately after the exercise protocol, the researchers took blood samples to measure serum creatine kinase (CK) and lactate dehydrogenase (LDH) levels, both indicators of the muscle tissue damage associated with soreness. “High plasma activity of CK and LDH enzymes is commonly used as indicators of muscle tissue damage. It has been demonstrated that these muscle enzymes enter the bloodstream when muscle cells are damaged,” the authors wrote.
     
    The placebo group had an average 124.3 U/L CK concentration at baseline, which increased to 332.4 post-test concentration of CK – significantly higher than the increase seen in the supplementation group (122.6 U/L to 211.6 U/L).
     
    At baseline, the placebo group had 311.4 U/L LDH concentrations, compared to 424.2 U/L at baseline. The supplementation group only increased from 304.8 to 323.1 U/L of LDH after the exercise protocol.
     
    Following the protocol, an intergroup comparison of the data indicated a significant decrease in both CK ad LDH  in the supplement group compared to the placebo group, with this difference achieving clinical significance only after the exercise took place.
     
    “The results of this study showed that HMB-FA supplementation reduced muscle injury indices,” the authors of the study noted, but this didn’t result in a significant change to the aerobic fitness index (VO2max) in the short term.
     
    While this study did not evaluate possible mechanisms of action, one proposed mechanism for further investigation is that HMB-FA may work by increasing the proliferation and differentiation of satellite cells in fast-twitch fibers, which would increase hypertrophy and alter muscle function. This process also promotes mitochondrial evolution and fat oxidation, according to the authors. Another possible mechanism of action is that supplementation increases the mTOR pathway activation, and increased IGF-1 expression -  the combined pathways are studied for their role in reducing protein breakdown and promoting muscle protein synthesis.
     
    According to TSI Group, the suppliers of the HMB ingredient MyHMB, DOMS is most common in people taking part in exercises which they aren’t accustomed to, and often gets worse before it gets better after initial onset over a period of about one or two days.
     
    “DOMS can happen at any age and to just about anyone,” said Shawn Baier, MS, MBA, vice president of business development for TSI Group, said. “It can happen whenever you’re engaged in an activity that you’re not used to doing, and that pushes you beyond your usual threshold, be that shoveling snow for the first time in early winter, or suddenly increasing the intensity of workouts.”
     
    Across the sum of clinical studies, HMB appears to act through two mechanisms of action, according to Baier. “Its known mechanism of action is to increase protein synthesis and minimize protein breakdown. This dual mechanism has been known to blunt damage to the muscles, meaning that there’s less energy and time required for your body to recover, and you can get back to training harder and sooner. There’s a lot of talk about this on social media from hardcore athletes and weekend warriors.”  
     
    Related Searches
    • Research
    • Dietary Supplements
    • Sports Nutrition
    Related Knowledge Center
    • Research
    • Sports Nutrition
    • Dietary Supplements
    Suggested For You
    Kyowa Hakko Publishes First Report on Global Health, Sustainability Impact Kyowa Hakko Publishes First Report on Global Health, Sustainability Impact
    Tocotrienol Supplementation May Aid Liver Function in Diabetes, MASL Patients Tocotrienol Supplementation May Aid Liver Function in Diabetes, MASL Patients
    CRN-International Announces New Publication Identifying Global Nutrient Gaps CRN-International Announces New Publication Identifying Global Nutrient Gaps
    State of the Industry Series (Part 1): FDA Restructuring and FTC Activity State of the Industry Series (Part 1): FDA Restructuring and FTC Activity
    State of the Industry Part 2: Supplement Access, Safety, and CBD State of the Industry Part 2: Supplement Access, Safety, and CBD
    State of the Industry Part 3: Communication, Education, and Trust State of the Industry Part 3: Communication, Education, and Trust
    How Can the Nutraceuticals Industry Empower More Women? How Can the Nutraceuticals Industry Empower More Women?
    Kyowa Hakko Discussed Cognitive Health Supplements at Neuro Navigators Event Kyowa Hakko Discussed Cognitive Health Supplements at Neuro Navigators Event
    Acme-Hardesty Achieves EcoVadis Silver Medal Acme-Hardesty Achieves EcoVadis Silver Medal
    FoodChain ID, ReSeed Partner on Transparency Program for Sustainable Practices FoodChain ID, ReSeed Partner on Transparency Program for Sustainable Practices
    IMMUSE Postbiotic Helps Orchestrate Comprehensive, Year-Round Immune Support IMMUSE Postbiotic Helps Orchestrate Comprehensive, Year-Round Immune Support
    Jiaherb Receives Organic Certification for New Farm and Facility in China Jiaherb Receives Organic Certification for New Farm and Facility in China
    The High Cost of Consumer Confusion: An Elderberry Case Study The High Cost of Consumer Confusion: An Elderberry Case Study
    Balchem Corporation Partners with American Nutrition Association Balchem Corporation Partners with American Nutrition Association
    Tomato Carotenoids Linked to Improved Skin Barrier Function and Elasticity Tomato Carotenoids Linked to Improved Skin Barrier Function and Elasticity

    Related Breaking News

    • Breaking News | Dietary Supplements | Supplier News | World Markets
      Kyowa Hakko Publishes First Report on Global Health, Sustainability Impact

      Kyowa Hakko Publishes First Report on Global Health, Sustainability Impact

      The 2023 CSV Progress Report details the company’s activities and policies, in line with the United Nations’ Sustainable Development Goals.
      12.05.23

    • Breaking News | Diabetes & Blood Sugar Management | Dietary Supplements | Medical Nutrition | Research News | Vitamins
      Tocotrienol Supplementation May Aid Liver Function in Diabetes, MASL Patients

      Tocotrienol Supplementation May Aid Liver Function in Diabetes, MASL Patients

      A pilot trial on 34 participants found that treatment with tocotrienols was associated with improved liver enzymes, fatty liver, and liver stiffness.
      12.04.23

    • Breaking News | Dietary Supplements | Healthcare Trends | Industry & Market News | Medical Nutrition
      CRN-International Announces New Publication Identifying Global Nutrient Gaps

      CRN-International Announces New Publication Identifying Global Nutrient Gaps

      The report summarizes findings from its annual Scientific Symposium in Germany.
      12.04.23


    • Dietary Supplements | Regulations
      State of the Industry Series (Part 1): FDA Restructuring and FTC Activity

      State of the Industry Series (Part 1): FDA Restructuring and FTC Activity

      FDA’s ongoing reorganization is among the most critical industry issues today.
      By Sean Moloughney, Editor 12.04.23

    • Dietary Supplements | Herbs & Botanicals | Quality & Safety | Regulations | Weight Management/Weight Loss
      State of the Industry Part 2: Supplement Access, Safety, and CBD

      State of the Industry Part 2: Supplement Access, Safety, and CBD

      State and federal regulators have taken aim at certain products and ingredients.
      By Sean Moloughney, Editor 12.04.23

    Loading, Please Wait..
    Breaking News
    • Women in Nutraceuticals Hires Executive Director Rebecca Takemoto
    • FDA Issues Interim Response to Nammex’s Mushroom Labeling Petition
    • MSM Linked to Improvements in Knee Pain
    • Lion’s Mane Extract Linked to Better Cognitive Performance, Subjective Stress
    • NutraShure Introduces SA3X as Exclusive US Supplier
    View Breaking News >
    CURRENT ISSUE

    December 2023

    • State of the Industry Series (Part 1): FDA Restructuring and FTC Activity
    • State of the Industry Part 2: Supplement Access, Safety, and CBD
    • State of the Industry Part 3: Communication, Education, and Trust
    • State of the Industry Part 4: Advanced/Advancing Technologies and Research
    • State of the Industry Part 5: Advocating Best Practices
    • State of the Industry Part 6: Business Trends and Innovation
    • Radicle Science Aims to Set New Trajectory for Healthcare with Modern Clinical Trial Model
    • How Can the Nutraceuticals Industry Empower More Women?
    • The Naturally Proud Network: Supporting Diversity, Equity, and Inclusion
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Women in Nutraceuticals Hires Executive Director Rebecca Takemoto
    FDA Issues Interim Response to Nammex’s Mushroom Labeling Petition
    MSM Linked to Improvements in Knee Pain
    Coatings World

    Latest Breaking News From Coatings World

    Weekly Recap: PPG, PPG Asian Paints, AkzoNobel Top This Week’s Stories
    Orion S.A. Has Four Carbon Black Plants Awarded ISCC PLUS
    Peninsula Polymers Acquires New Distribution Center in Indiana
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most-Read Stories This Week—Dec. 9
    Babson Diagnostics’ BetterWay Achieves Regulatory Milestone
    WhiteSwell Successfully Treats Acute Decompensated Heart Failure in Study
    Contract Pharma

    Latest Breaking News From Contract Pharma

    FDA Approves Bio-Thera's Biosimilar Referencing Roche’s Avastin
    Full-Life Technologies to Build GMP Radiopharmaceuticals Mfg. Facility
    Innovent Biologics, Synaffix Expand ADC Licensing Deal
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    COSRX’s Latest TikTok Campaign Accumulates 3.2B Views on TikTok
    Christian Louboutin Taps Morgane Martini as Global Makeup Artist
    Shiseido Forms New Venture Fund
    Happi

    Latest Breaking News From Happi

    Diya Beauty & Wellness Acquires WR Group's Retail Brands and North American Sales Division
    Pantone Color of the Year & A New CEO
    When It Comes to Bath and Body Rituals, Consumers Want The Works
    Ink World

    Latest Breaking News From Ink World

    Weekly Recap: Siegwerk, DIC, and Müller Martini Top This Week’s Stories
    Orion S.A. Now Has Four Carbon Black Plants Awarded ISCC PLUS
    BASF Commits to Scope 3.1 Emissions Targets
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Analyzing the Russian label market, Cartes boosts brands and more
    FLAG’s December Lunch & Learn to feature Omet
    UPM Raflatac releases neuromarketing study findings
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Weekly Recap: New Dates for INDEX 26, Campen Announces Patent Pending Status for Airlaid Trays
    Ginni Strikes Deal to Sell Spinning, Knitting Operations
    Campen Machinery Announces Patent Pending Status for Airlaid Trays
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—Dec. 9
    Fujitsu, iSurgery Launch Bone Health Promotion Project in Japan
    Wenzel Spine Hires Dr. Robert Gordon as Executive Chairman
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Weekly Recap: Schreiner MediPharm, GIANCE and PragmatIC Top This Week’s Stories
    Intel CEO Pat Gelsinger to Cover AI During CES 2024 Keynote
    Ciena Invests in US Manufacturing with Flex

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login