• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain

    Jordan Process Receives Nutrasource ICAP Certification for CBD
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Gencor

    KLK OLEO

    Xsto Solutions

    Nutrition21, LLC

    Aiya America, Inc. (Aiya Matcha)
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Gencor

    KLK OLEO

    Xsto Solutions

    Nutrition21, LLC

    Aiya America, Inc. (Aiya Matcha)
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Curcumin Extract Shows Benefit, Reduces Analgesic Use in Osteoarthritis Patients

    In a group of 101 OA patients, improvements were seen in both self-reported pain and performance based metrics.

    Curcumin Extract Shows Benefit, Reduces Analgesic Use in Osteoarthritis Patients
    Related CONTENT
    • Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
    • Jordan Process Receives Nutrasource ICAP Certification for CBD
    • Solabia Algitech will Showcase Its Algae-Based Ingredients
    • Environmental, Social and Governance in the Cannabis Industry: A Perfect Storm is Brewing
    • Fullscript Drives Consolidation While Eyeing Inroads to Conventional Care
    01.19.22
    Supplementation with a curcumin extract marketed by DolCas Biotech as Curcugen was linked to multiple positive outcomes in a pool of 101 osteoarthritis patients in a new double-blind, randomized, placebo-controlled trial published in Nutrients.
     
    Specifically, patients who took the extract, which is standardized to contain 50% curcuminoids, saw improvements in performance-based metrics, reductions in self-reported pain, and reported that they were using pain relieving medication significantly less than their counterparts in the control group.
     
    Osteoarthritis (OA) is a disease of the whole joint, comprising structural alterations in the articular cartilage, subchondral bone, ligaments, capsule, synovial membrane, and periarticular muscles. While many studies in the past have found curcumin supplementation to be helpful in cases of arthritis, few have actually included functional assessments of joint performance to reduce evaluation biases.
     
    So, the authors included performance-based testing, in addition to other measures such as the Knee Injury and Osteoarthritis Outcome Score (KOOS), knee pain ratings, Japanese Orthopedic Association Score for Osteoarthritic Knees (JOA), and PROMIS–29, a quality-of-life assessment.
     
    When it came to more subjective measures of pain, the authors of the study noted that KOOS data showed a statistically significant improvement – KOOS scores averaged out to 11.98 for the curcumin group, well above the average score of 5.52 seen in the placebo group at week 8. The JOA assessment, which is observer-led, also showed clinically-meaningful differences in the curcumin group compared to placebo.
     
    Noteworthy to the investigators was the fact that in the group receiving the 500mg twice-daily supplement, 19 of the 51 were able to decrease their analgesic medication by the endpoint of the study eight weeks later, compared to only six participants in the equally-sized placebo group (at baseline, 49% and 53% of participants in the placebo and curcumin groups respectively took pain relieving medication).
     
    Importantly, the authors also noted significant differences between the two groups on performance-based metrics. Compared to the placebo, curcumin supplementation was associated with significantly greater improvements in a timed up-and-go test, a six-minute walk test, and scores in JOA, which involves scoring based on observations of walking ability, stair climbing, joint function, and pain. No significant differences were observed for the 30-second chair stand test or the 40-meter fast-paced walk test, however.
     
    “The results of this trial identified a standard level of translatability to larger audiences, which compares very well with other studies in the area of knee joint pain. The data has been obtained for Curcugen to identify it as a promising, well-tolerated, and naturally-derived joint-support option,” said Adrian L. Lopresti, PhD, principal investigator of the study.
     
    The overall blend of natural turmeric constituents is vital to Curcugen’s formulation, Dr. Shavon Jackson-Michel, director of medical and scientific affairs for DolCas Biotech, said. “In contrast to certain generic curcumin products, Curcugen’s unique formulation preserves the original complex of curcuminoids, essential oils and polar resins within a natural matrix. These naturally-occurring constituents synergistically increase curcumin bioavailability and, as supported by this trial, its efficacy in the treatment of OA of the knee.
     
    “The point I find most interesting in this study is its evaluation of the Minimal Clinical Important Difference (MCID),” Jackson-Michel added. “It’s an outcome that’s considered to be meaningful for the patients themselves and, as such, is both clinically important and elevates the results above simple statistical significance.”
     
    An average MCID of 33% was recorded for participants taking Curcugen compared to 19% in the placebo group, she noted.
    Related Searches
    • Dietary Supplements
    • Bone & Joint Health
    • Inflammation
    • Healthy Aging
    Related Knowledge Center
    • Natural/Organic
    • Delivery & Dosage Technologies
    • Dietary Supplements
    Suggested For You
    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
    Jordan Process Receives Nutrasource ICAP Certification for CBD Jordan Process Receives Nutrasource ICAP Certification for CBD
     Solabia Algitech will Showcase Its Algae-Based Ingredients Solabia Algitech will Showcase Its Algae-Based Ingredients
    Fullscript Drives Consolidation While Eyeing Inroads to Conventional Care Fullscript Drives Consolidation While Eyeing Inroads to Conventional Care
    Environmental, Social and Governance in the Cannabis Industry: A Perfect Storm is Brewing Environmental, Social and Governance in the Cannabis Industry: A Perfect Storm is Brewing
    Market Shifts in Joint and Muscle Health Market Shifts in Joint and Muscle Health
    Curcumin Ingredient Curcugen Sees Positive Results in Safety Study Curcumin Ingredient Curcugen Sees Positive Results in Safety Study
    Arla Foods Ingredients Receives Positive Novel Food Opinion for BLG Arla Foods Ingredients Receives Positive Novel Food Opinion for BLG
    ChromaDex Launches Tru Niagen Immune ChromaDex Launches Tru Niagen Immune
    Natural Products Expo West Returns: Product Spotlight Natural Products Expo West Returns: Product Spotlight
    Digestive, Gut Health Solutions Offer Downstream Benefits Digestive, Gut Health Solutions Offer Downstream Benefits
    Bridging Gaps in Women’s Health with Renewed Attention Bridging Gaps in Women’s Health with Renewed Attention
    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research Beyond CBD: Cannabis Compounds Warrant Recognition and More Research
    Sugar Content Claim Litigation on the Rise Sugar Content Claim Litigation on the Rise
    Cannabis Sales Predicted to Surpass $61 Billion Globally by 2026 Cannabis Sales Predicted to Surpass $61 Billion Globally by 2026

    Related Content

    • Breaking News | Diabetes & Blood Sugar Management | Industry & Market News | Medical Nutrition
      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

      The American College of Lifestyle Medicine, with multi-organizational support, said that plant-predominant diets can achieve remission ahead of other treatment.
      05.19.22

    • Breaking News | Certifications, Approvals & Patents | Herbs & Botanicals | Quality & Safety | Testing
      Jordan Process Receives Nutrasource ICAP Certification for CBD

      Jordan Process Receives Nutrasource ICAP Certification for CBD

      The company was the first raw material provider to join the certification program.
      05.18.22

    •  Solabia Algitech will Showcase Its Algae-Based Ingredients

      Solabia Algitech will Showcase Its Algae-Based Ingredients

      The company's astaxanthin-rich microalgae ingredients are marketed for antioxidant activity and sports nutrition applications.
      05.05.22


    • Dietary Supplements | Healthcare Trends | Herbs & Botanicals | Natural/Organic | Regulations | World Markets
      Environmental, Social and Governance in the Cannabis Industry: A Perfect Storm is Brewing

      Environmental, Social and Governance in the Cannabis Industry: A Perfect Storm is Brewing

      Marc Ross discusses how companies getting in front of ESG are well-positioned to win investors, talent, and customers.
      By Sheldon Baker, CEO Baker Dillon Group LLC 05.03.22

    • Dietary Supplements | Healthcare Trends | Medical Nutrition | Regulations
      Fullscript Drives Consolidation While Eyeing Inroads to Conventional Care

      Fullscript Drives Consolidation While Eyeing Inroads to Conventional Care

      The DOJ reviewed and cleared the deal to acquire Emerson Ecologics. What’s it mean for brands and the future of the practitioner channel?
      By Erik Goldman, Holistic Primary Care 05.03.22

      Trending
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk In Older Adults | Nutraceuticals World
      • Leaven Essential To Launch Branded Botanical Extracts To Global Markets | Nutraceuticals World
      • Indena’s Meriva Curcumin Supplement May Benefit Kidney Function
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults
      • Test On Hydrolyzed Collagen Shows Resoundingly High Bioavailability | Nutraceuticals World
      Breaking News
      • Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
      • Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
      • Choline Alone May Improve Maternal DHA Status During Pregnancy
      • Cranberry Consumption Linked to Memory and Neurological Function Improvements
      • Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
      Choline Alone May Improve Maternal DHA Status During Pregnancy
      Coatings World

      Latest Breaking News From Coatings World

      Teknos Receives EcoVadis Gold Medal for Sustainability Performance
      AkzoNobel and Partners Team Up to Hack Carbon Reduction Challenges
      Five PPG Facilities in Ohio Recognized for Sustainability, Health, Safety Practices
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      Prometheus Group Sued Over Reused Catheters and Rectal Sensors
      VenoStent's SelfWrap Bioabsorbable Perivascular Wrap Earns Breakthrough Status
      Guard Medical Closes $11 Million Series B Investment
      Contract Pharma

      Latest Breaking News From Contract Pharma

      Catalent Invests $175M to Expand Mfg. Capabilities at Winchester, KY
      Sartorius Expands Manufacturing Site in Tunisia
      BioMoti Partners with Pharma Company to Develop Ovarian Cancer Treatment
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      Garance Doré Launches Made in France Skincare Line
      The World’s Most Popular Perfumes & Celebrity Fragrances
      Ulta Beauty Launches Retail Media Network
      Happi

      Latest Breaking News From Happi

      Estée Lauder Companies' New Research on Oxidative Damage, Skin Barrier Function & Hyperpigmentation
      Lush Gay is OK Soap Supports Equality Florida
      Crown Laboratories Appoints New GM of Premium Skincare Business Unit
      Ink World

      Latest Breaking News From Ink World

      hubergroup Chemicals Exhibits at Paint India for First Time
      Award for Sustainability: Evonik Receives Platinum Rating Again
      Nazdar Ink Technologies to Showcase Latest Ink Innovations at FESPA Global Print Expo 2022
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      Dantex Group receives accreditation for Pico digital presses
      Heidelberg USA launches new Print Media Performance & Training Center
      Avery Dennison announces Global Supplier Award winners
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      'Right' Hygiene Conference to be Held in June
      Freudenberg to Present Battery Pack and Liquid Absorbers at Battery Show
      H&V Appoints Vice President and General Counsel
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      FDA Clears Anika Therapeutics' X-Twist Knotless Fixation System
      Paragon 28 Rolls Out TenoTac 2.0 Hammertoe and Soft Tissue Repair
      Cionic Expands Scientific Advisory Board
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      Evonik Launches New Processing Aids for PV Wafer Cutting
      NREL Creates Highest Efficiency 1-Sun Solar Cell
      eMagin Wins People’s Choice Award at Display Week 2022

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login