• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

    Cargill’s Stevia Sustainability Program Benchmarked by FSA

    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Beyond Raw Launches Concept X Pre-Workout Line

    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    KLK OLEO

    ESHA Research

    Applied Food Sciences, Inc.

    Sabinsa Corporation

    Ecuadorian Rainforest
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    KLK OLEO

    ESHA Research

    Applied Food Sciences, Inc.

    Sabinsa Corporation

    Ecuadorian Rainforest
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Animal Study Suggests Melatonin Metabolite May Improve Memory

    Researchers concluded that a melatonin metabolite may one day be used therapeutically for age-related cognitive decline.

    Animal Study Suggests Melatonin Metabolite May Improve Memory
    While melatonin can impair or improve memory depending on when it's taken, one of its metabolites appeared to be much more effective at all times of day.
    Related CONTENT
    • Thorne Relaunches Gut Health Test with Microbiome Wipe
    • Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
    • Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort
    • Choline Alone May Improve Maternal DHA Status During Pregnancy
    • Cranberry Consumption Linked to Memory and Neurological Function Improvements
    12.23.20
    Melatonin, long studied for sleep and cognitive support, was shown in a recent animal trial published in the Journal of Pineal Research to benefit long-term object memory in a group of young and aging mice. Specifically, researchers identified melatonin metabolites, AMK and AFMK, as being responsible for the improvements to memory, due to the high levels which were present in the hippocampus and frontal lobe of the mice during the experiment.
     
    The findings suggest that one day, AMK and AFMK therapies could be shown in clinical trials to be beneficial for age-related memory issues, such as mild cognitive impairment, a precedent to more serious conditions such as Alzheimer’s disease and dementia.
     
    Mice at the ages of 2 months, 14 months, and 21 months were used in order to assess the impact of melatonin metabolites on young, middle-aged, and old animal models. The animals were trained to perform a number of acquisition trials in order to assess long-term memory formation, with time spent exploring the novel environments calculated in sequential tests.
     
    The researchers found that a single treatment with melatonin, or either of the two metabolites studied, “remarkably facilitated [long-term memory] in mice.” It likely reflected processes that follow memory encoding, they said, based on the relatively short-half lives of these nutrients, suggesting that their role is primarily in the formation of memory.
     
    “As the most potent LTM facilitating compound, our next set of experiments focused on the role of AMK in memory consolidation and encoding,” the authors said. “AK administered 60 minutes before to 120 minutes after training enhanced LTM, indicating its broad temporal effects on LTM at a 1 mg/kg dose.”
     
    Acute melatonin administration appeared to have either an impaired or improved cognitive performance, the researchers said, which was dependent upon the time of day at which dosage occurred.
     
    “In conclusion, we provide the first evidence that acute treatment with AMK, a melatonin metabolite, facilitates long-term memory with superior effects compared to melatonin,” the researchers concluded. “The present data strongly suggest that AMK plays a key role in facilitating short-term memory-to-long-term memory transfer of information.”
    Related Searches
    • Research
    • Dietary Supplements
    • Cognitive Function
    Related Knowledge Center
    • Research
    • Cognitive Function
    • Dietary Supplements
    Suggested For You
    Thorne Relaunches Gut Health Test with Microbiome Wipe Thorne Relaunches Gut Health Test with Microbiome Wipe
    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort
    Choline Alone May Improve Maternal DHA Status During Pregnancy Choline Alone May Improve Maternal DHA Status During Pregnancy
    Cranberry Consumption Linked to Memory and Neurological Function Improvements Cranberry Consumption Linked to Memory and Neurological Function Improvements
    Consumer Conviction: Results of consumer satisfaction study on mental wellness and sleep. Consumer Conviction: Results of consumer satisfaction study on mental wellness and sleep.
    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    GNC Adds Products from The Honest Company, Hers, and Womaness GNC Adds Products from The Honest Company, Hers, and Womaness
    Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds
    Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds
    Indena Spotlights ‘Fabulous Four’ Ingredients Indena Spotlights ‘Fabulous Four’ Ingredients
    Hofseth BioCare’s CalGo Ingredient Shown to be More Absorbable than Calcium Carbonate Hofseth BioCare’s CalGo Ingredient Shown to be More Absorbable than Calcium Carbonate
    Lonza Expands Capsugel Capsule Offering with Titanium Dioxide-Free, White Hard Gelatin Capsules Lonza Expands Capsugel Capsule Offering with Titanium Dioxide-Free, White Hard Gelatin Capsules
    Open Book Extracts Completes Phase 1 of Toxicology, Safety Assessment for Cannabinoid Ingredients Open Book Extracts Completes Phase 1 of Toxicology, Safety Assessment for Cannabinoid Ingredients
    Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults

    Related Content

    • Digestive Health | Testing
      Thorne Relaunches Gut Health Test with Microbiome Wipe

      Thorne Relaunches Gut Health Test with Microbiome Wipe

      This first-to-market approach to testing makes stool sampling for the personalized test more user-friendly.
      05.24.22

    • Digestive Health | Immune Function | Probiotics & Prebiotics | Research
      Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

      Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

      Two graduate students were awarded $50,000 in grants from the annual gut microbiome, yogurt, and probiotics-focused program.
      05.24.22

    • Antioxidants | Breaking News | Dietary Supplements | Herbs & Botanicals | Inflammation | Research News | Supplier News
      Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

      Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

      The novel combination of moringa seed extract and Sunfiber was tested in 40 healthy adults.
      05.23.22


    • Breaking News | Dietary Supplements | Infant & Children's Health | Medical Nutrition | Research News | Vitamins | Women's Health
      Choline Alone May Improve Maternal DHA Status During Pregnancy

      Choline Alone May Improve Maternal DHA Status During Pregnancy

      Independently of additional DHA intake, choline supplementation resulted in higher DHA status in maternal and umbilical cord blood.
      05.19.22

    • Antioxidants | Breaking News | Cognitive Function | Herbs & Botanicals | Medical Nutrition | Research News
      Cranberry Consumption Linked to Memory and Neurological Function Improvements

      Cranberry Consumption Linked to Memory and Neurological Function Improvements

      The vascular health benefits of cranberries may have a role to play in neurological improvements, according to the authors.
      05.19.22

      Trending
      • Leaven Essential To Launch Branded Botanical Extracts To Global Markets | Nutraceuticals World
      • Oregon Files Lawsuit Against GNC | Nutraceuticals World
      • Coca-Cola To Phase Out Honest Tea Brand By Year’s End, Citing Supply Chain Challenges | Nutraceuticals World
      Breaking News
      • Thorne Relaunches Gut Health Test with Microbiome Wipe
      • Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
      • GC Rieber Foundations Expand Philanthropic Efforts
      • Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
      • Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Thorne Relaunches Gut Health Test with Microbiome Wipe
      Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
      GC Rieber Foundations Expand Philanthropic Efforts
      Coatings World

      Latest Breaking News From Coatings World

      Nippon Paint Automotive Americas Appoints Robert Angart CEO and President
      Sustainability, Economy are Focus of BCF’s Annual Conference
      Demand for Rhino Shield Increases
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      MPO's Most-Read Stories This Week—May 28
      New Breast Implant Surgery Guidelines to Enhance Patient Safety
      Rhythm Management Group Debuts RhythmSynergy Tech Platform
      Contract Pharma

      Latest Breaking News From Contract Pharma

      iECURE Enters Agreement with Center for Breakthrough Medicines
      CPDC Enters Clinical Manufacturing Deal with CellBion
      Olon to Build New R&D Center in Italy
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      K-Beauty Brand Siita Shares Plastic Decomposition Technology with the Beauty Industry
      Shellworks Raises $6.2 Million in Seed Funding
      Ulta Beauty Reports Record First Quarter 2022 Results
      Happi

      Latest Breaking News From Happi

      Honeywell Addresses Critical Issues Such as Sustainability, Workforce Training and Digitalization
      Monat Global Wins Four Stevie Awards in the 20th Annual American Business Awards
      Coty Expands Vegan Beauty Portfolio With New Rimmel Mascara
      Ink World

      Latest Breaking News From Ink World

      Weekly Recap: Flint Group, New Inks from Siegwerk and Zeller+Gmelin Lead This Week’s News
      Orion to Finish Gas Black Expansion in Germany by Early 2023
      Richard Childress Racing Shows Off New Wraps for 2022 NASCAR Season
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      UPM Raflatac accelerates label growth with acquisition
      Labelexpo Asia 2022 postponed
      Teklynx software helps Top Clean Injection validate labels
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      Rael Raises $35M in Series B Funding
      Schobertechnologies Offers Rotary Web-fed Converting Solutions
      Thorne Relaunches Gut Health Test with Microbiome Wipe
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      ODT's Most-Read Stories This Week—May 28
      Toetal Solutions Raises $1.02 Million in New Financing
      ManaMed's ManaSport Wearable Ultrasound Earns FDA Nod
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      Weekly Recap: OPV’s Future, Graphene Flagship and Japan Display Top This Week’s Stories
      SEMI Foundation Receives $1.5 Million Grant to Bolster Michigan’s Semiconductor Talent Pipeline
      onsemi Recognized by Fortune 500 for Its Transformation Journey

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login