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    Breaking News

    Australian Study Discovers New Genetic Expressions Triggered by Seaweed Extract

    Fucoidan, a complex polysaccharide, is found in many species of brown seaweed.

    Australian Study Discovers New Genetic Expressions Triggered by Seaweed Extract
    Could fucoidan's ability to alter gene expression one day be used for therapeutic purposes?
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    • Researchers Review Therapeutic Benefits of Fucoidan
    03.06.20
    A recent study which appeared in the journal Marine Drugs is furthering the scientific intrigue in fucoidan, a seaweed extract known for its potential to alter genetic expression in humans.
     
    An Australian clinical study has revealed that an extract from the seaweed Undaria pinnatifida influences over 30 different biological pathways and processes.
     
    In the first worldwide clinical trial of its kind, the placebo-controlled, double blind pilot study demonstrated that the unique polysaccharide fucoidan, derived from brown macroalgae, affects microRNA composition in the plasma of healthy individuals. The results support the known inhibitory effects of fucoidan in inflammation, cancer and neurological disorders.
     
    The analysis found that nine additional pathways and processes that had not previously been associated with fucoidan before. “Overall, this study illustrates that even a single dose of fucoidans has the potential to affect the expression of genes related to fundamental cellular processes,” the study authors wrote.    
     
    Blood samples were taken immediately before, and 24 hours after, ingestion of either a single dose of fucoidan or a placebo.
     
    MicroRNAs are widely studied as biomarkers over a wide range of health indications including cancer, cardiovascular disease, obesity and inflammation. They are small RNA molecules known to regulate gene expression. In some cases, a direct pathological function has been established providing the opportunity to utilize them as therapeutic targets.
     
    Results of the study demonstrated that fucoidan can alter regulatory microRNA in healthy individuals. Furthermore, they showed that even a single dose of fucoidan has the potential to affect the expression of genes related to fundamental cellular processes.
     
    The study also confirmed previous published findings demonstrating that fucoidan has beneficial effects on immunity, cancer cells, inflammation and neurological function. In particular, analysis of the fucoidan-induced changes in serum microRNA substantiated the known anti-cancer effects of fucoidan. The BDNF (brain-derived neurotrophic factor) signaling pathway was also shown to be affected, supporting the previously documented antidepressant effects of fucoidan.
     
    Nine additional pathways and processes were identified that have not previously been associated with fucoidan. These include renal cancer and circadian rhythm.
     
    “This new clinical research not only confirms previous data demonstrating that fucoidan has beneficial effects on immunity, cancer cells, inflammation and neurological function, but provides insight into new pathways not formerly associated with fucoidan,” Dr. Helen Fitton, co-author of the paper and chief scientist at Marinova, said. “These are exciting results that further increase the potential for fucoidan to be utilized in a wider range of therapeutic treatments.”
     
    The fucoidan utilized in the study was Maritech fucoidan, manufactured by Australian biotechnology company Marinova.
     
     
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    • Breaking News | Dietary Supplements | Immune Function | Marine Nutraceuticals | Natural/Organic | Research | Research News | World Markets
      Clinical Trial on Maritech Fucoidan will Further Investigate Possible Immune Benefits

      Clinical Trial on Maritech Fucoidan will Further Investigate Possible Immune Benefits

      Clincial and preclinical evidence currently reports that the brown seaweed extract can support immune function at a cellular level and possibly reduce infection rates for certain viruses.
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    • Breaking News | Immune Function | Marine Nutraceuticals | Research News | Sports Nutrition | Supplier News
      Seaweed Extract Shown to Support Immune Function of Elite Athletes

      Seaweed Extract Shown to Support Immune Function of Elite Athletes

      Following fucoidan supplementation, lysozyme concentrations (a marker of mucosal immune function) increased by 45%.
      08.06.20

    • Breaking News | Marine Nutraceuticals | Research | Research News | Supplier News
      Researchers Review Therapeutic Benefits of Fucoidan

      Researchers Review Therapeutic Benefits of Fucoidan

      Summary details use of fucoidan to treat renal disease, the radiolabeling of blood clots, and the increased use in supplements.
      10.25.19

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