NAFLD is a spectrum of disorders ranging from steatosis, non-alcoholic steatohepatitis (NASH), fibrosis, and cirrhosis of the liver. It is also commonly associated with metabolic syndrome and cardiovascular diseases. The American Liver Foundation estimates at least 25% of the U.S. population has NAFLD.
The peer-reviewed paper published in the Journal of Cellular Biochemistry, 2019; 120: 15989-reported on the efficacy of C3 Complex combined with Sabinsa’s bioavailability enhancer BioPerine on NAFLD subjects in a randomized controlled parallel-group clinical trial.
The decrease in the severity of NAFLD in the subjects was gauged by hepatic sonography, and significant improvement was observed in several elevated liver function parameters such as ALT, ASP, and ALP in NAFLD subjects treated with the C3 Complex and BioPerine combination. NAFLD severity was reduced in a statistically significant way in the treatment group compared to the placebo group. No adverse effect on the hematological parameters were found, showing the safety of the ingredients.
“We're encouraged by the researchers’ conclusion that combined supplementation of C3 Complex and BioPerine may provide a safe and viable method for curtailing the progress of NAFLD,” said Sabinsa founder Dr. Muhammed Majeed.