• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    A Clearer Path to Weight Management: The Ozempic Factor

    Under Pressure: Stress and Mental Health Have Taken Center Stage

    Sustainable Business Development: Principles and Strategies for Progress

    Beauty IO MarketWatch: L’Oréal to Define the Next Era of Beauty Tech in CES 2024 Keynote

    Introducing the Happi & Nutraceuticals World Wellness Conference & Tabletop Exhibition
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Glossary
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    GOED Releases Sustainability Report for Omega-3s Industry

    ABC’s Journal HerbalGram Celebrates 40th Anniversary

    Curcumin May Be As Effective as PPI for Indigestion

    Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies

    Women in Nutraceuticals Launches Pilot Mentorship Program
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    GOED Releases Sustainability Report for Omega-3s Industry

    ABC’s Journal HerbalGram Celebrates 40th Anniversary

    Curcumin May Be As Effective as PPI for Indigestion

    Weight Loss Products Sold as Supplements Adulterated with Toxic Yellow Oleander

    Nature’s Way Canada Launches NutraSea Omega-3 Kids Chews
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    GOED Releases Sustainability Report for Omega-3s Industry

    ABC’s Journal HerbalGram Celebrates 40th Anniversary

    Curcumin May Be As Effective as PPI for Indigestion

    Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies

    Women in Nutraceuticals Launches Pilot Mentorship Program
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Curcumin May Be As Effective as PPI for Indigestion

    Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies

    Weight Loss Products Sold as Supplements Adulterated with Toxic Yellow Oleander

    Nature’s Way Canada Launches NutraSea Omega-3 Kids Chews

    Kyowa Hakko's Immuse Postbiotic Introduced to Mexican Market
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Sabinsa Corporation

    Aiya America, Inc. (Aiya Matcha)

    Applied Food Sciences, Inc.

    PhytoGaia Inc

    KLK OLEO
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Sabinsa Corporation

    Aiya America, Inc. (Aiya Matcha)

    Applied Food Sciences, Inc.

    PhytoGaia Inc

    KLK OLEO
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    California Proposes Listing Goldenseal Root and Whole-Leaf Aloe Vera as Carcinogens Under Prop 65

    AHPA president says proposed classification relied on uncritical reviews of research on animals.

    04.29.15
    California's Office of Environmental Health Hazard Assessment (OEHHA) announced on April 23 its intent to list Aloe vera whole-leaf extract and goldenseal root powder as chemicals "known to the state to cause cancer" under Proposition 65 (the Safe Drinking Water and Toxic Enforcement Act of 1986). Limited comments may be submitted by May 26.

    The OEHHA announcement stated that these listings are proposed pursuant to the "Labor Code listing mechanism" and are based on classification of these substances in 2013 by the International Agency for Research on Cancer (IARC) in its Group 2B, "possibly carcinogenic to humans." OEHHA views the Labor Code mechanism as requiring an automatic "ministerial" listing and states it "cannot consider scientific arguments concerning the weight or quality of the evidence considered by IARC when it identified these chemicals and will not respond to such comments if they are submitted."

    Products that present exposure to chemicals listed by California as known to the state to cause cancer generally require specific warnings on such products sold in California, though there are several exemptions, including for foods in which a listed chemical is naturally occurring or when an exposure is below an established "no significant risk level." Failure to provide such warnings can result in action by the California attorney general or by "any person in the public interest."

    The OEHHA announcement identified whole leaf extract of Aloe vera as "the liquid portion of the Aloe vera leaf," and importantly clarifies that this substance "is not the same as Aloe vera decolorized whole leaf extract, Aloe vera gel, Aloe vera gel extract, or Aloe vera latex, which would not be covered by this proposed listing." OEHHA also identified whole leaf extract of Aloe vera as "a natural constituent of Aloe barbadensis," a synonymous name for Aloe vera.

    OEHHA identified goldenseal root powder as "the powdered dried roots and underground stems of goldenseal plants" (Hydrastis canadensis) and declared it to be "a natural constituent of the goldenseal plant."

    "IARC's classification of these two herbal ingredients relied on uncritical reviews of research conducted by the National Toxicology Program wherein laboratory animals were fed extremely large doses on a daily basis for almost their entire lifetimes," said Michael McGuffin, president of the American Herbal Products Association (AHPA). "A further complication in NTP's study of aloe is that it used an ingredient—a nondecolorized extract of Aloe vera leaf—that appears to be only marginally available in the market, and OEHHA is correctly confirming that the substance proposed for listing is not the same as the more commonly found Aloe vera decolorized whole leaf extract or Aloe vera gel."

    In its report on its two-year study on goldenseal root powder, NTP stated that "clear evidence of carcinogenic activity" was observed in male and female rats that were fed as much as the equivalent for a human of over a pound a week of goldenseal root. The report also stated it is "a hazard identification rather than a risk assessment document" and further noted, "Extrapolation of these results to other species, including characterization of hazards and risks to humans, requires analyses beyond the intent of these reports."

    "NTP's communication of the gap between its hazard identification and determination of human risk appears to have been lost on IARC," noted Mr. McGuffin. "And although OEHHA has stated that it does not believe it has any obligation to consider any additional scientific information, AHPA will submit comments to call attention to the flaws in this so-called ministerial process.”
    Related Searches
    • Cancer
    • Research
    • Natural
    • Health
    Related Knowledge Center
    • Quality & Safety
    • Regulations
    Suggested For You
    Supplement Orgs Respond to Congressional Request for Information on CBD Supplement Orgs Respond to Congressional Request for Information on CBD
    CBD and Pet Health: Wellness for Our Four-Legged Friends CBD and Pet Health: Wellness for Our Four-Legged Friends
    Select Immune Supplements On Amazon Fail to Meet Label Specifications Select Immune Supplements On Amazon Fail to Meet Label Specifications
    Ingestible Beauty Arrives in China Ingestible Beauty Arrives in China
    Digestive, Gut Health Solutions Offer Downstream Benefits Digestive, Gut Health Solutions Offer Downstream Benefits
    Desert Harvest Commits to Phasing Out Plastic Bottles for All Supplements Desert Harvest Commits to Phasing Out Plastic Bottles for All Supplements
    Unigen Launches Immune, Respiratory Health Ingredients Unigen Launches Immune, Respiratory Health Ingredients
    Beauty Ingredient Formulation Directory Fall 2021 Beauty Ingredient Formulation Directory Fall 2021
    Natural Products Association Joins Coalition for Accurate Product Labels Natural Products Association Joins Coalition for Accurate Product Labels
    AHPA Issues White Paper on Good Herbal Compounding & Dispensing Practices AHPA Issues White Paper on Good Herbal Compounding & Dispensing Practices
    AHPA & LifeScienceRisk Develop Prop 65 Insurance Coverage AHPA & LifeScienceRisk Develop Prop 65 Insurance Coverage
    AHPA Developing Assessment Program for Agricultural, Collection & Manufacturing Practices AHPA Developing Assessment Program for Agricultural, Collection & Manufacturing Practices
    AHPA Awards Recognize Substantive Contributions to Industry AHPA Awards Recognize Substantive Contributions to Industry
    Prop 65 Warning Required for Aloe & Goldenseal Effective Dec. 4 Prop 65 Warning Required for Aloe & Goldenseal Effective Dec. 4
    AHPA Reappoints Ayurvedic Products Committee AHPA Reappoints Ayurvedic Products Committee

    Related Breaking News

    • Herbs & Botanicals | Regulations
      Supplement Orgs Respond to Congressional Request for Information on CBD

      Supplement Orgs Respond to Congressional Request for Information on CBD

      Interested parties are invited to provide data and commentary regarding a regulatory fix for CBD and hemp-derived cannabinoid products.
      08.18.23

    • Consumer Trends | Healthcare Trends | Natural/Organic | Pet Nutraceuticals
      CBD and Pet Health: Wellness for Our Four-Legged Friends

      CBD and Pet Health: Wellness for Our Four-Legged Friends

      Health and wellness are reasons behind the popularity of CBD-containing tinctures, treats, and topicals designed for dogs and cats.
      By Christine Esposito, Managing Editor, Happi 04.13.23

    • Herbs & Botanicals | Immune Function | Quality & Safety | Testing | Vitamins
      Select Immune Supplements On Amazon Fail to Meet Label Specifications

      Select Immune Supplements On Amazon Fail to Meet Label Specifications

      Testing found only about a third of labels for featured products making immune health claims accurately reflected product contents.
      By Mike Montemarano, Associate Editor 09.15.22


    • Consumer Trends | Cosmeceuticals / Nutricosmetics | Healthcare Trends | Minerals | Regulations | Skin Health | Vitamins | World Markets
      Ingestible Beauty Arrives in China

      Ingestible Beauty Arrives in China

      Demand soars as regulations become clearer and younger consumers have an appetite for tablets, capsules, and drinks.
      By Ally Dai, Contributing Writer 09.01.22

    • Cardiovascular Health | Dietary Supplements | Digestive Health | Herbs & Botanicals | Minerals | Probiotics & Prebiotics
      Digestive, Gut Health Solutions Offer Downstream Benefits

      Digestive, Gut Health Solutions Offer Downstream Benefits

      Unique ingredients and understanding of their mechanisms can help formulators deliver products that address numerous pain points.
      By Sean Moloughney, Editor 04.14.22

    Loading, Please Wait..
    Trending
    • Soviets Took Probiotics To The Next Level
    • New Technology Converts Sugar In Juice To Fiber
    • Shiitake Mushroom Extract Appears Helpful In HPV Infections
    • SmartX: Poised For Cerebral Success
    • Curcumin May Be As Effective As PPI For Indigestion
    Breaking News
    • GOED Releases Sustainability Report for Omega-3s Industry
    • ABC’s Journal HerbalGram Celebrates 40th Anniversary
    • Curcumin May Be As Effective as PPI for Indigestion
    • Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies
    • Women in Nutraceuticals Launches Pilot Mentorship Program
    View Breaking News >
    CURRENT ISSUE

    September 2023

    • A Clearer Path to Weight Management: The Ozempic Factor
    • Under Pressure: Stress and Mental Health Have Taken Center Stage
    • Sustainable Business Development: Principles and Strategies for Progress
    • BIOHM Health Targets ‘Digestive Plaque’ with Probiotic, Fungus, and Enzyme Formula
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    GOED Releases Sustainability Report for Omega-3s Industry
    ABC’s Journal HerbalGram Celebrates 40th Anniversary
    Curcumin May Be As Effective as PPI for Indigestion
    Coatings World

    Latest Breaking News From Coatings World

    Nouryon Manufacturing Network Transitions to 100% Electricity From Renewable Sources in Brazil
    Jay Doubman Named President and CEO of ICP Group
    “MyCarbonFootprint”: BASF Launches Dashboard for Sustainable Procurement
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Beckman Coulter Helping Labs Comply With Annex 1 Regulation
    FDA Clears MeMed BV Direct From Whole Blood
    Biostrap Debuts Tool to Measure Stress Resilience, Heart Rate Variability
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Eftilagimod Cleared for Clinical Trial Use in the UK
    Veranova Names William Sanders Global VP of Chemical Development Ops
    Chime, Panolos Partner to Advance Multi-specific Therapeutic Proteins
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Hailey Bieber's Rhode Expands Into Makeup
    Avon Enters Retail Partnership with Superdrug
    IT Award Winners Announced at MakeUp in NY
    Happi

    Latest Breaking News From Happi

    Divi Expands in Stores at Ulta Beauty Tripling Footprint
    Huda Beauty Adds Easy Bake and Snatch Pressed Brightening and Setting Powder
    Detergent for Baby Bottles Contains an Odor Absorber
    Ink World

    Latest Breaking News From Ink World

    INKBANK Lays Foundation for Science and Technology Park
    Successful Labelexpo Europe 2023 Concludes in Brussels
    Recyclable, Deinkable Stand-Up Pouch Wins Gold
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Flexo Wash to exhibit at FTA Fall Technical Conference
    Recyclable, deinkable stand-up pouch wins Gold in Germany
    Elkem highlights thermal protection and battery assembly products
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Lenzing Earns EU Ecolabel at Indonesian Plant
    Albis Completes Work On Extra Wide Carding, Blending Line
    Ahlstrom Launches Nonwoven Laundry Care Product
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Anika Releases RevoMotion Reverse Shoulder Arthroplasty System
    Exactech's Activit-E Polyethylene OK'ed for Vantage Total Ankle
    Tyber Nets Several Regulatory Nods for K-Wires, Steinmann Pins
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    HMI Specialist RAFI Acquires Xymox Technologies Inc.
    Infineon Heads EECONE European Research Project
    NXP Honored with Prestigious Automotive Awards

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login