The high rate of Osteoporosis in the population have made bone and joint health products very popular in the current market. Osteoporosis has been recognized as a systematic metabolic skeletal disease that generally worsens with age, women’s fertility, and menopause. According to statistics from the World Health Organization, more than 200 million individuals are affected with osteoporosis-ranking it as seventh among worldwide common afflictions. About 40 million people in the United States are threatened by osteoporosis, placing the U.S. at the forefront of the bone and joint health industry. Dietary bone health supplements on the market often contain a large amount of calcium, magnesium, minerals, and vitamins that can help osteoporosis, but often have low absorption rates when consumed. Traditional Vitamin D3 and K2 can also help improve calcium absorption, but the improvement is limited. An imperative exists to find more effective and safer solutions to meet the growing demand on bone health market.