Regulations

Natreon’s Crominex 3+ Granted GRAS Approval

Crominex 3+ is a trivalent chromium supplement.

By: Lisa Olivo

Natreon, New Brunswick, NJ has been granted GRAS approval for Crominex 3+ (Trivalent chromium polyphenolic complex).
 
Crominex 3+ is a trivalent chromium supplement prepared by complexing trivalent chromium chloride with two natural products, Phyllanthus emblica (Capros) and purified Shilajit (PrimaVie) in order to minimize the conversion of chromium III to toxic chromium VI. Crominex 3+ is designed to give content uniformity in finished dosage forms.
 
Two recent studies, which are currently pending publication, have shown that Crominex 3+ is much more efficacious than all the other branded chromium products (chromium picolinate, chromium polynicotinate and chromium dinicocysteinate) in reducing HbA1c levels and in improving cardiac risk factors (endothelial function, lipid profile, biomarkers of oxidative stress). In addition, it showed highly significant synergistic activity, according to the company, compared to the activity of the individual components. 

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