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Dose-dependent improvements in multiple self-reported and physiological symptoms were observed in 123 women.
March 31, 2025
By: Mike Montemarano
Associate Editor, Nutraceuticals World
Supplementation with Sensoril, an ashwagandha extract marketed by Kerry, or a Shatavari extract, was associated with dose-dependent improvements in self-reported menopausal symptoms in a population of 123 women, with changes first noted at 250 mg per day, per a new clinical study.
Hormonal changes can lead to symptoms like hot flashes, mood swings, and sleep disturbances, noted Kerry, which impact approximately 80% of post-menopausal women. Despite being so common, menopause is relatively understudied for its potential impact on aging.
“Women are looking for a proactive approach to wellbeing, where their specific health needs are understood and met with the right product at the right time, and Kerry is rising to the occasion,” said Monica Maria Olivares, PhD, RDA Director of Women’s & Infant Health at Kerry. “This study further supports the current and extensive research naming Sensoril a safe and effective solution. Driving progress in women’s health is of vital importance to us at Kerry, which is why we have curated a suite of naturally sourced and clinically studied ingredients that support women across every life stage.”
Participants in the study, all women between the ages of 40 and 55, were randomly enrolled to take a placebo, a shatavari (Asparagus racemosus) extract at either 250 or 500 mg, ashwagandha at either 250 or 500 mg, or a combination of the two ingredients at a dose of 250 mg each.
All groups were evaluated for changes in the menopause-specific quality of life questionnaire, along with physiological measures like bone mineral density/bone turnover markers, reflection index (a measure of vascular health), serum inflammatory and oxidative stress markers, and other safety indicators.
According to the authors, daily supplementation with either ashwagandha, shatavari, or both extracts was associated with improvements in self-reported menopause-related quality of life measures, bone mass, and vascular endothelial function after 24 weeks, in a dose-dependent manner.
The menopause questionnaire found significant improvements in supplementation groups in self-reported vasomotor symptoms like hot flashes, sweating, and night sweats; psychosocial symptoms like poor memory, anxious feelings, lower productivity, dissatisfaction with personal life, and more; physical symptoms related to sleep, fatigue, strength, stamina, energy, appearance, aches and pains, and more; and sexual health issues like intimacy avoidance.
As part of a broader focus on women’s health, Kerry launched HerWay, an online resource addressing women’s unique health and wellness experiences. HerWay houses key information on pressing health and wellness issues, as well as news regarding the latest market trends in women’s health.
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