Unigen Pharmaceuticals, Inc.

July 1, 2005

Unigen Pharmaceuticals, Inc., Lacey, WA, has been issued a composition of matter and usage patent for the company’s proprietary antioxidant ingredients contained in its Aloewhite and Pervarin commercial raw material ingredient products from the U.S. Patent and Trademark Office. Through the identification and purification of specific aloe chromones derived from aloe vera and other plant species, Unigen scientists have demonstrated the effectiveness of these chromones in inhibiting free radical and oxidative damage through the simultaneous suppression of free radical generation and production of Reactive Oxygen Species (ROS), which includes oxygen-related free radicals.