05.01.03
Indication: Glycemic and insulinemic response
Source: Med Sci Monit, 2003:9(2):CR84-90.
Research: A total of 20 healthy adult subjects were recruited to participate in a randomized trial investigating how energy bars of differing macronutrient composition affect postprandial glycemia and insulinemia in normal subjects compared with white bread and chicken breast controls. After an overnight fast, subjects were fed 60-gram portions of one of five meals, which were as follows: low carbohydrate bar (Atkins Advantage Bar, LC), moderate carbohydrate bar (Balance Bar, MC), high carbohydrate bar (Power Bar, HC), white bread (WB) and chicken breast (CHI). Capillary fingerstick and venous blood samples were analyzed for glucose and insulin concentrations, respectively, at baseline and at 15, 30, 45, 60, 90 and 120 minutes after the start of the test meal.
Results: Compared with WB, plasma glucose area under the curve (AUC) for the meals was 71% lower for the LC bar, 50% lower for the MC bar, 4% higher for the HC bar and 83% lower for the CHI. Serum insulin AUC, again compared with WB, was 26% lower for the LC bar, 35% higher for the MC bar, 73% higher for the HC bar and 78% lower for the CHI. According to researchers, this study demonstrated that the substitution of other macronutrients for carbohydrates is effective for reducing postprandial glycemia. However, the insulin response may not decrease to the same degree and, for some bars, may actually be elevated compared with WB.
Source: Med Sci Monit, 2003:9(2):CR84-90.
Research: A total of 20 healthy adult subjects were recruited to participate in a randomized trial investigating how energy bars of differing macronutrient composition affect postprandial glycemia and insulinemia in normal subjects compared with white bread and chicken breast controls. After an overnight fast, subjects were fed 60-gram portions of one of five meals, which were as follows: low carbohydrate bar (Atkins Advantage Bar, LC), moderate carbohydrate bar (Balance Bar, MC), high carbohydrate bar (Power Bar, HC), white bread (WB) and chicken breast (CHI). Capillary fingerstick and venous blood samples were analyzed for glucose and insulin concentrations, respectively, at baseline and at 15, 30, 45, 60, 90 and 120 minutes after the start of the test meal.
Results: Compared with WB, plasma glucose area under the curve (AUC) for the meals was 71% lower for the LC bar, 50% lower for the MC bar, 4% higher for the HC bar and 83% lower for the CHI. Serum insulin AUC, again compared with WB, was 26% lower for the LC bar, 35% higher for the MC bar, 73% higher for the HC bar and 78% lower for the CHI. According to researchers, this study demonstrated that the substitution of other macronutrients for carbohydrates is effective for reducing postprandial glycemia. However, the insulin response may not decrease to the same degree and, for some bars, may actually be elevated compared with WB.