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02.21.07
Indication: cholesterol (in overweight women)
Source:
American Journal of Clinical Nutrition, January 2007;85(1):54-9.
Research:
The objective of the study was to determine the effects of daily calcium intake and of supplementation with calcium and vitamin D (calcium+D) during a weight loss intervention trial on blood pressures, plasma lipid and lipoprotein concentrations, and glucose and insulin concentrations in low calcium consumers. For this researchers recruited 63 healthy, overweight or obese women with a daily calcium intake of less than 800 mg per day, who were randomly assigned in a double-blind manner to one of two groups: one consuming two tablets per day containing calcium + vitamin D (600 mg elemental calcium and 200 IU vitamin D per tablet) and one group consuming placebo-both groups observed a 700 kcal per day energy restriction. These 63 women then completed a 15-week weight loss intervention study.
Results:
After the 15-week intervention, significantly greater decreases in total:LDL and LDL:HDL and of LDL cholesterol were observed in the calcium+D group than in the placebo group. The differences in total:HDL and LDL:HDL were independent of changes in fat mass and in waist circumference. A tendency for more beneficial changes in HDL cholesterol, triacylglycerol, and total cholesterol was also observed in the calcium+D group. This evidence led researchers to conclude that consumption of calcium+D during a weight loss intervention enhanced the beneficial effect of body weight loss on the lipid and lipoprotein profile in overweight or obese women with usual low daily calcium intake.