07.29.11
A new meta-analysis published in the American Journal of Clinical Nutrition indicates dietary fiber may reduce the risk of breast cancer.
Researchers identified 10 prospective cohort studies of dietary fiber intake and risk of breast cancer involving 16,848 cases and 712,195 participants. The combined Relative Risk (RR) of breast cancer for the highest compared with the lowest dietary fiber intake was 0.89 (95% Confidence Interval: 0.83, 0.96), and little evidence of heterogeneity was observed.
The association between dietary fiber intake and risk of breast cancer did not significantly differ by geographic region, length of follow-up, or menopausal status of the participants, according to the study abstract. Omission of any single study little changed the combined risk estimate. Dose-response analysis showed that every 10-grams/day increment in dietary fiber intake was associated with a significant 7% reduction in breast cancer risk. Little evidence of publication bias was found.
Researchers concluded this meta-analysis provides evidence of a significant inverse dose-response association between dietary fiber intake and breast cancer risk.
Researchers identified 10 prospective cohort studies of dietary fiber intake and risk of breast cancer involving 16,848 cases and 712,195 participants. The combined Relative Risk (RR) of breast cancer for the highest compared with the lowest dietary fiber intake was 0.89 (95% Confidence Interval: 0.83, 0.96), and little evidence of heterogeneity was observed.
The association between dietary fiber intake and risk of breast cancer did not significantly differ by geographic region, length of follow-up, or menopausal status of the participants, according to the study abstract. Omission of any single study little changed the combined risk estimate. Dose-response analysis showed that every 10-grams/day increment in dietary fiber intake was associated with a significant 7% reduction in breast cancer risk. Little evidence of publication bias was found.
Researchers concluded this meta-analysis provides evidence of a significant inverse dose-response association between dietary fiber intake and breast cancer risk.