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  • Phytonutrients Poised for Growth

    Joanna Cosgrove || January 1, 2007
    A new report sheds light on the hopes and hindrances of this age-old segment.

  • WEB EXCLUSIVE: To IND or not to IND

    Joanna Cosgrove || January 1, 2007
    Taking the IND route with botanical ingredients is not a journey for the faint of heart or light of funded.

  • Top 10 Predictions for 2007

    Top 10 Predictions for 2007

    January 1, 2007
    10. It's no secret that consumers have become quite complex. Those that read National Geographic don't necessarily listen to National Public Radio or have an interest in joining the Sierra Club-they might listen to Howard Stern and not have a care in…

  • ProEPA/EPA Supplement Reduces Anxiety in Adults with History of Substance Abuse

    January 1, 2007
    A recent double-blind, placebo-controlled, randomized trial published in the Journal of Clinical Psychopharmacology is one of the first to demonstrate benefits of fish oil in adults with anxiety and a history of substance abuse, according to Nordic N…

  • Alternative therapies

    January 1, 2007
    Indication: High cholesterol Source: Annals of Pharmacotherapy, November 2006;40(11)1984-92. Research: Researchers from Kaiser Permanente of Colorado reviewed the literature on select alternative therapies for the management of dyslipidemia. Se…

  • Pycnogenol

    January 1, 2007
    Indication: Edema Source: Clin Appl Thromb Hemost, October 2006;12(4):440-4. Research: This study sampled 53 hypertensive patients at the G D’annunzio University in Italy. All patients suffered from edema of their ankles and feet as a re…

  • Chocolate nutrition bar (CocoaVia)

    January 1, 2007
    Indication: Cholesterol lowering Source: Journal of the American Dietetic Association, November 2006;106:1804-1813. Research: Sixty-seven men and women with elevated cholesterol (>200 mg/dl total cholesterol) were randomly assigned to one o…

  • Docosahexaenoic acid (DHA)

    January 1, 2007
    Indication: Alzheimer’s disease Source: Archives of Neurology, November 11, 2006;63(11):1527-1528. Research: Researchers set out to study the association between dementia and DHA status among 899 men and women who were part of the Framing…

  • Nestlé to Fund Brain Research

    January 1, 2007
    The Nestlé Research Center (NRC), Lausanne, Switzerland, and EPFL (one of the two Swiss Federal Institutes of Technology) have signed a five-year agreement to conduct research on the relationship between nutrition and the brain. Under this agr…

  • Vitamin D

    December 11, 2006
    Indication: Breast cancer Source: J Clin Pathol., October 17, 2006;Epub ahead of print. Research: Laboratory and epidemiological studies have implicated vitamin D deficiency in the pathogenesis of breast cancer. This was the impetus for researc…

  • Plant sterols

    December 11, 2006
    Indication: Heart disease risk factors Source: American Journal of Clinical Nutrition, October 2006;84(4):756-761. Research: In a previous study, researchers were able to show that supplementation with orange juice containing plant sterols (2 g…

  • Milk thistle

    December 11, 2006
    Indication: Diabetes Source: Phytotherapy Research, October 30, 2006;published online ahead of print. Research: Researchers conducted a study on 51 diabetics to determine the effects of milk thistle, and specifically an active constituent (flav…

  • Curcumin

    December 11, 2006
    Indication: Cognitive function Source: American Journal of Epidemiology, November 2006;164(9):898-906. Research: Curcumin, from the curry spice turmeric, has been shown to possess potent antioxidant and anti-inflammatory properties and to reduc…

  • B Vitamins

    December 11, 2006
    Indication: Heart disease Source: American Journal of Clinical Nutrition, October 2006;84(4):880-887. Research: Laboratory and observational studies suggest that antioxidant and B vitamin supplementation may prevent atherosclerosis. Although t…

  • Proprietary Perspective: Exclusivity Agreement: Exclude the Bad & Exalt the Good

    Anthony Almada, B.Sc. || December 1, 2006
    As the dearth of blockbuster bioactives continues, the drive to inflate the small into the superior and the new into allowed proceeds unabated.

  • Hitting Bottom

    Hitting Bottom

    December 1, 2006
    More regulation is not only a possibility, but most certainly a reality for the future of dietary supplements and functional foods. Let's start with dietary supplements. Authorities, from Congress to FDA to FTC and down the line, in my opinion, have…

  • Research Highlights

    December 1, 2006
    Dermylex Relieves Psoriasis Symptoms A recently completed randomized, double-blind placebo-controlled clinical trial of Advitech, Inc.’s (Quebec, Canada) Dermylex supplement has demonstrated the product’s measurable impact on relieving p…

  • Research Highlights

    December 1, 2006
    High Genistein Supplement Effective in Reducing Hot Flashes In 2005, a group of scientists undertook a critical review of published studies that looked at isoflavone extracts and their effectiveness in reducing frequency or severity of menopausal…

  • Vitamin D

    December 1, 2006
    Indication: Breast cancer Source: J Clin Pathol., October 17, 2006;Epub ahead of print. Research: Laboratory and epidemiological studies have implicated vitamin D deficiency in the pathogenesis of breast cancer. This was the impetus for researc…

  • Plant sterols

    December 1, 2006
    Indication: Heart disease risk factors Source: American Journal of Clinical Nutrition, October 2006;84(4):756-761. Research: In a previous study, researchers were able to show that supplementation with orange juice containing plant sterols (2 g…

  • Milk thistle

    December 1, 2006
    Indication: Diabetes Source: Phytotherapy Research, October 30, 2006;published online ahead of print. Research: Researchers conducted a study on 51 diabetics to determine the effects of milk thistle, and specifically an active constituent (flav…

  • Curcumin

    December 1, 2006
    Indication: Cognitive function Source: American Journal of Epidemiology, November 2006;164(9):898-906. Research: Curcumin, from the curry spice turmeric, has been shown to possess potent antioxidant and anti-inflammatory properties and to reduc…

  • B Vitamins

    December 1, 2006
    Indication: Heart disease Source: American Journal of Clinical Nutrition, October 2006;84(4):880-887. Research: Laboratory and observational studies suggest that antioxidant and B vitamin supplementation may prevent atherosclerosis. Although tr…

  • Soy isoflavones

    November 6, 2006
    Indication: Lipoprotein levels (postmenopausal women) Source: Menopause, Oct 2, 2006;[Epub ahead of print]. Research: Some clinical trials have demonstrated a beneficial effect of dietary soy protein on improving lipoproteins. Research has a…

  • Potassium citrate

    November 6, 2006
    Indication: Bone density (postmenopausal women) Source: Journal of the American Society of Nephrology, October 11, 2006: doi: 10.1681/ASN.2006030233 (online ahead of print). Research: Chronic acid loads are an obligate consequence of the…

  • Omega 3 fatty acids

    November 6, 2006
    Indication: Alzheimer's disease (AD) Source: Arch Neurol, October 2006;63:1402-1408. Research: Epidemiologic and animal studies have suggested that dietary fish or fish oil rich in omega 3 fatty acids, for example, docosahexaenoic acid (D…

  • Plant stanols

    November 6, 2006
    Indication: High cholesterol Source: J Am Diet Assoc, October 2006;106(10):1564-9. Research: Plant stanols have been recommended in combination with individualized dietary interventions to reduce plasma cholesterol concentrations. However…

  • Green tea

    November 6, 2006
    Source: JAMA, September 13, 2006;296:1255-1265. Research: Green tea polyphenols have been extensively studied as cardiovascular disease and cancer chemopreventive agents in vitro and in animal studies. However, the effects of green tea consumpti…

  • Calcium

    November 6, 2006
    Indication: Bone health (children) Source: Osteoporos Int., Sep 22, 2006;[Epub ahead of print]. Research: Calcium supplementation enhances bone mass accrual during administration, with a sustained benefit observed using milk-based calcium…

  • The Research Process: Beyond the Clinical Trial

    Douglas Kalman || November 1, 2006
    Market research can be just as important as scientific proof in harnessing consumer purchasing power.

  • A Case of Mistaken Identity

    A Case of Mistaken Identity

    November 1, 2006
    I have been watching the events with Berkeley Premium Nutraceuticals unfold over the past few years, not because it is one of the highest profile supplement cases in recent memory, but because I have been on the receiving end of numerous customer com…

  • Research Highlights

    November 1, 2006
    Diosmin Helps Improve Diabetic Vascular Conditions New research has shown improvement in microcirculatory disorders experienced by diabetic patients that were treated with Daflon 500 mg—a fraction flavonoid, 90% of which is comprised of the s…

  • Research Highlights

    November 1, 2006
    Research Highlights LinumLife Proven Bioavailable A recent human clinical pilot study conducted by the Kanda Ishin Clinic in Tokyo, Japan, has shown that flax lignans from Acatris’ LinumLife product are biovailable. This research demonstrat…

  • Research Highlights

    November 1, 2006
    Pycnogenol Relieves Muscle Cramps and Pain in Athletes A study published in Angiology has showed that supplementation with Horphag Research’s Pycnogenol pine bark extract improves blood flow to the muscles, which speeds recovery after physica…

  • Soy isoflavones

    November 1, 2006
    Indication: Lipoprotein levels (postmenopausal women) Source: Menopause, Oct 2, 2006;[Epub ahead of print]. Research: Some clinical trials have demonstrated a beneficial effect of dietary soy protein on improving lipoproteins. Research has als…

  • Potassium citrate

    November 1, 2006
    Indication: Bone density (postmenopausal women) Source: Journal of the American Society of Nephrology, October 11, 2006: doi: 10.1681/ASN.2006030233 (online ahead of print). Research: Chronic acid loads are an obligate consequence of the high…

  • Omega 3 fatty acids

    November 1, 2006
    Indication: Alzheimer’s disease (AD) Source: Arch Neurol, October 2006;63:1402-1408. Research: Epidemiologic and animal studies have suggested that dietary fish or fish oil rich in omega 3 fatty acids, for example, docosahexaenoic acid (…

  • Plant stanols

    November 1, 2006
    Indication: High cholesterol Source: J Am Diet Assoc, October 2006;106(10):1564-9. Research: Plant stanols have been recommended in combination with individualized dietary interventions to reduce plasma cholesterol concentrations. However, res…

  • Green tea

    November 1, 2006
    Source: JAMA, September 13, 2006;296:1255-1265. Research: Green tea polyphenols have been extensively studied as cardiovascular disease and cancer chemopreventive agents in vitro and in animal studies. However, the effects of green tea consumptio…

  • Calcium

    November 1, 2006
    Indication: Bone health (children) Source: Osteoporos Int., Sep 22, 2006;[Epub ahead of print]. Research: Calcium supplementation enhances bone mass accrual during administration, with a sustained benefit observed using milk-based calcium but…

  • Verdure to Focus on Bionutritional Research; Acquires Geni Herbs' Branded Ingredients

    November 1, 2006
    Verdure to Focus on Bionutritional Research; Acquires Geni Herbs’ Branded Ingredients Verdure Sciences, Indianapolis, IN, has developed plans to focus on the research and development of innovative bionutritionals. With the main focus on resear…

  • Vitamins

    October 13, 2006
    Indication: Pre-eclampsia Source: American Journal of Epidemiology, September 2006;164(5):470-477. Research: The objective of this study was to assess the independent effect of regular periconceptional (before pregnancy) multivitamin use o…

  • Vitamin E and zinc

    October 13, 2006
    Indication: Asthma (children) Source: Am J Respir Crit Care Med, Sep 1, 2006;174(5):499-507. Research: In the past, researchers have made an association between reduced maternal vitamin E intake during pregnancy and wheezing in two-year-…

  • Traditional Chinese Medicine preparation

    October 13, 2006
    Indication: Irritable bowel syndrome (IBS) Source: American Journal of Gastroenterology, July 24, 2006;101(7):1574. Research: According to the investigators in this study, there is no effective treatment for IBS, which is why some patients…

  • Prebiotics

    October 13, 2006
    Indication: Eczema Source: Archives of Diseases in Childhood, Epub ahead of print, July, 27 2006;doi:10.1136/adc.2006.098251. Research: Researchers wanted to find out if adding prebiotics to infant formula would encourage the growth of ben…

  • Chromium picolinate (CrPic)

    October 13, 2006
    Indication: Weight gain and glycemic control Source: Diabetes Care, August 2006;29(8):1826-32. Research: Thirty-seven subjects with type 2 diabetes were evaluated in a 40-week study. After baseline, subjects were placed on a sulfonylurea…

  • Lutein and zeaxanthin

    October 13, 2006
    Indication: Intermediate age-related macular degeneration Source: Arch Ophthalmol, August 2006;124:1151-1162. Research: Investigators were interested in evaluating the relationship between dietary lutein plus zeaxanthin and intermediate ag…

  • Fruit or vegetable juice

    October 13, 2006
    Indication: Alzheimer's disease Source: Am J Med, September 2006;119(9):751-759. Research: Researchers tested whether consumption of fruit and vegetable juices, containing a high concentration of polyphenols, decreases the risk of inciden…

  • DHA

    October 13, 2006
    Indication: Infant visual acuity Source: Congress for the International Society for the Study of Fatty Acids and Lipids (ISSFAL), Cairns, Australia-July 2006 Research: In this double-blind, randomized study, 100 pregnant women received a…

  • Proprietary Perspective: Weighting for Godot

    Anthony Almada, B.Sc. || October 1, 2006
    The wait for a weight loss bioactive marvel demands patience, risk tolerance, and investment, while many industrial players prefer to eschew patience and mitigate risk by resigning to commodity platforms that are often unsustainable.